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Lipid-coated albumin-paclitaxel nanoparticles loaded with sorcin-siRNA reverse cancer chemoresistance via restoring intracellular calcium ion homeostasis
Chemoresistance is often a cause of the failure of chemotherapy in cancer treatment. Sorcin (SRI) is a soluble resistance-related calcium-binding protein involved in chemoresistant processes and is overexpressed in many chemoresistant cancer cells, including paclitaxel (PTX)-resistant ovarian cancer...
Autores principales: | Wang, Chenglong, Xu, Xiaolin, Zhang, Peipei, Xiong, Shuhan, Yuan, Jia, Gao, Xuzhu, Guan, Wencai, Wang, Fanchen, Li, Xin, Dou, Hongjing, Xu, Guoxiong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264675/ https://www.ncbi.nlm.nih.gov/pubmed/35799174 http://dx.doi.org/10.1186/s12951-022-01487-6 |
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