Halting the Canadian STRIDER randomised controlled trial of sildenafil for severe, early-onset fetal growth restriction: ethical, methodological, and pragmatic considerations

OBJECTIVES: To determine the efficacy and safety of sildenafil citrate to improve outcomes in pregnancies complicated by early-onset, dismal prognosis, fetal growth restriction (FGR). Eligibility: women ≥ 18 years, singleton, 18 + 0–27 + 6 weeks’ gestation, estimated fetal weight < 700 g, low PLF...

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Detalles Bibliográficos
Autores principales: von Dadelszen, Peter, Audibert, François, Bujold, Emmanuel, Bone, Jeffrey N., Sandhu, Ash, Li, Jing, Kariya, Chirag, Chung, Youkee, Lee, Tang, Au, Kelvin, Skoll, M. Amanda, Vidler, Marianne, Magee, Laura A., Piedboeuf, Bruno, Baker, Philip N., Lalji, Sayrin, Lim, Kenneth I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264704/
https://www.ncbi.nlm.nih.gov/pubmed/35799272
http://dx.doi.org/10.1186/s13104-022-06107-y

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