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Effects of end-stage osteoarthritis on markers of skeletal muscle Long INterspersed Element-1 activity

OBJECTIVE: Long INterspersed Element-1 (L1) is an autonomous transposable element in the genome. L1 transcripts that are not reverse transcribed back into the genome can accumulate in the cytoplasm and activate an inflammatory response via the cyclic GMP-AMP (cGAS)-STING pathway. We examined skeleta...

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Detalles Bibliográficos
Autores principales:	Osburn, Shelby C., Romero, Matthew A., Roberson, Paul A., Mumford, Petey W., Wiggins, Derek A., McAdam, Jeremy S., Drummer, Devin J., Bridges, S. Louis, Bamman, Marcas M., Roberts, Michael D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264706/ https://www.ncbi.nlm.nih.gov/pubmed/35799274 http://dx.doi.org/10.1186/s13104-022-06113-0

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