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1,25-dihydroxyvitamin D3 ameliorates lupus nephritis through inhibiting the NF-κB and MAPK signalling pathways in MRL/lpr mice

BACKGROUND: Lupus nephritis (LN) is a common and serious complication of systemic lupus erythematosus (SLE). However, the aetiology and pathogenesis of LN remain unknown. 1,25-dihydroxyvitamin D3 [1,25-(OH)2-VitD3] is the active form of vitamin D, and it has been shown to perform important functions...

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Detalles Bibliográficos
Autores principales: Li, Xuewei, Liu, Jie, Zhao, Yingzhe, Xu, Ning, Lv, E., Ci, Chunzeng, Li, Xiangling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264719/
https://www.ncbi.nlm.nih.gov/pubmed/35804318
http://dx.doi.org/10.1186/s12882-022-02870-z

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