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Porcine reproductive and respiratory syndrome virus non-structural protein 4 cleaves guanylate-binding protein 1 via its cysteine proteinase activity to antagonize GBP1 antiviral effect

Porcine reproductive and respiratory syndrome (PRRS) is a highly infectious disease caused by PRRS virus (PRRSV) that causes great economic losses to the swine industry worldwide. PRRSV has been recognized to modulate the host antiviral interferon (IFN) response and downstream interferon-stimulated...

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Detalles Bibliográficos
Autores principales:	Duan, Hong, Dong, Haoxin, Wu, Shuya, Ren, Jiahui, Zhang, Mingfang, Chen, Chuangwei, Du, Yongkun, Zhang, Gaiping, Zhang, Angke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264745/ https://www.ncbi.nlm.nih.gov/pubmed/35804432 http://dx.doi.org/10.1186/s13567-022-01071-8

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