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Testing for Dihydropyrimidine Dehydrogenase Deficiency to Individualize 5-Fluorouracil Therapy

SIMPLE SUMMARY: 5-Fluorouracil (5-FU) is a chemotherapy drug that is commonly used to treat multiple cancers. Many people who are treated with 5-FU experience severe toxicity to the drug, and in severe cases, patients can die. This review discusses current methods for identifying people who are at h...

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Detalles Bibliográficos
Autores principales: Diasio, Robert B., Offer, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264755/
https://www.ncbi.nlm.nih.gov/pubmed/35804978
http://dx.doi.org/10.3390/cancers14133207