Preferential Antibody and Drug Conjugate Targeting of the ADAM10 Metalloprotease in Tumours

SIMPLE SUMMARY: ADAM10 is a cell surface protein that releases other proteins from cells, thereby controlling a range of functions during normal development. Its activity is normally tightly regulated, but it can become deregulated in cancer calls. We previously showed that an active form of ADAM10...

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Detalles Bibliográficos
Autores principales: Yan, Hengkang, Vail, Mary E., Hii, Linda, Guo, Nancy, McMurrick, Paul J., Oliva, Karen, Wilkins, Simon, Saha, Nayanendu, Nikolov, Dimitar B., Lee, Fook-Thean, Scott, Andrew M., Janes, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264901/
https://www.ncbi.nlm.nih.gov/pubmed/35804938
http://dx.doi.org/10.3390/cancers14133171

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