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Genome-Wide CRISPR Screening Identifies DCK and CCNL1 as Genes That Contribute to Gemcitabine Resistance in Pancreatic Cancer

SIMPLE SUMMARY: Pancreatic cancer is one of the most lethal cancers. Although complete surgical resection is the only curative treatment for pancreatic cancer, a late diagnosis is common and makes surgical treatment infeasible. Therefore, most patients receive chemotherapy to reduce the tumor burden...

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Detalles Bibliográficos
Autores principales: Yang, Hai, Liu, Bin, Liu, Dongxue, Yang, Zhirong, Zhang, Shuman, Xu, Pengyan, Xing, Yuming, Kutschick, Isabella, Pfeffer, Susanne, Britzen-Laurent, Nathalie, Grützmann, Robert, Pilarsky, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264918/
https://www.ncbi.nlm.nih.gov/pubmed/35804923
http://dx.doi.org/10.3390/cancers14133152