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Deregulation of Cholesterol Homeostasis by a Nuclear Hormone Receptor Crosstalk in Advanced Prostate Cancer

SIMPLE SUMMARY: Metastatic castration-resistant prostate cancer (mCRPC) is one of the leading causes of cancer-related death. mCRPC tumors feature high intratumoral cholesterol levels. Our current study shows that the nuclear receptor RORγ plays crucial roles in the aberrant cholesterol homeostasis...

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Detalles Bibliográficos
Autores principales:	Yang, Nianxin, Yang, Yatian, Huang, Zenghong, Chen, Hong-Wu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265016/ https://www.ncbi.nlm.nih.gov/pubmed/35804882 http://dx.doi.org/10.3390/cancers14133110

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