Cargando…

Dysregulated Immune and Metabolic Microenvironment Is Associated with the Post-Operative Relapse in Stage I Non-Small Cell Lung Cancer

SIMPLE SUMMARY: The underlying mechanism of post-operative relapse of non-small cell lung cancer (NSCLC) remained poorly understood. This study highlights that both tumors and adjacent tissues from stage I NSCLC with relapse show a dysregulated immune and metabolic environment. Immune response shift...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Shirong, Xiao, Xiao, Zhu, Xiuli, Chen, Xueqin, Zhang, Xiaochen, Xiang, Jingjing, Xu, Rujun, Shao, Zhuo, Bai, Jing, Xun, Yanping, Jiang, Yanping, Chen, Zhengzheng, Xia, Xuefeng, Jiang, Hong, Ma, Shenglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265031/ https://www.ncbi.nlm.nih.gov/pubmed/35804832 http://dx.doi.org/10.3390/cancers14133061

Ejemplares similares

Association between plasma somatic copy number variations and response to immunotherapy in patients with programmed death-ligand 1-negative non-small cell lung cancer
por: Zhang, Xiaochen, et al.
Publicado: (2022)

Epidermal growth factor receptor (EGFR) T790M mutation identified in plasma indicates failure sites and predicts clinical prognosis in non-small cell lung cancer progression during first-generation tyrosine kinase inhibitor therapy: a prospective observational study
por: Zhang, Shirong, et al.
Publicado: (2018)

Increased MIR31HG lncRNA expression increases gefitinib resistance in non-small cell lung cancer cell lines through the EGFR/PI3K/AKT signaling pathway
por: Wang, Bing, et al.
Publicado: (2017)

Comprehensive profiling and quantitation of oncogenic mutations in non small-cell lung carcinoma using single molecule amplification and re-sequencing technology
por: Zhang, Shirong, et al.
Publicado: (2016)

Rechallenge with gefitinib following severe drug-induced hepatotoxicity in a patient with advanced non-small cell lung cancer: A case report and literature review
por: CHEN, XUEQIN, et al.
Publicado: (2014)

Suberoylanilide hydroxamic acid enhances the radiosensitivity of lung cancer cells through acetylated wild-type and mutant p53-dependent modulation of mitochondrial apoptosis
por: Wu, Kan, et al.
Publicado: (2021)

Capilliposide C from Lysimachia capillipes Restores Radiosensitivity in Ionizing Radiation-Resistant Lung Cancer Cells Through Regulation of ERRFI1/EGFR/STAT3 Signaling Pathway
por: Wu, Kan, et al.
Publicado: (2021)

Dysregulation of B7 family and its association with tumor microenvironment in uveal melanoma
por: Chen, Yao, et al.
Publicado: (2022)

Integrated Analysis of Genomic and Immunological Features in Lung Adenocarcinoma With Micropapillary Component
por: Zhang, Shirong, et al.
Publicado: (2021)

The Dysregulation of SOX Family Correlates with DNA Methylation and Immune Microenvironment Characteristics to Predict Prognosis in Hepatocellular Carcinoma
por: Qin, Sha, et al.
Publicado: (2022)

Genome-wide profiling reveals alternative polyadenylation of mRNA in human non-small cell lung cancer
por: Zhang, Shirong, et al.
Publicado: (2019)

An immune-related microRNA signature prognostic model for pancreatic carcinoma and association with immune microenvironment
por: Shen, Qian, et al.
Publicado: (2022)

Immunological Dysregulation in Multiple Myeloma Microenvironment
por: Romano, Alessandra, et al.
Publicado: (2014)

Identifies microtubule-binding protein CSPP1 as a novel cancer biomarker associated with ferroptosis and tumor microenvironment
por: Wang, Wenwen, et al.
Publicado: (2022)

Glasgow prognostic score predicts prognosis of non-small cell lung cancer: a meta-analysis
por: Zhu, Lucheng, et al.
Publicado: (2016)

Antibacterial intraosseous implant surface coating that responds to changes in the bacterial microenvironment
por: Bai, Xin, et al.
Publicado: (2023)

免疫检查点抑制剂相关不良反应预测的研究进展
por: ZHANG, Jing, et al.
Publicado: (2023)

Strategies to overcome DC dysregulation in the tumor microenvironment
por: Mestrallet, Guillaume, et al.
Publicado: (2022)

Self-powered user-interactive electronic skin for programmable touch operation platform
por: Zhao, Xuan, et al.
Publicado: (2020)

Immunotherapy of targeting MDSCs in tumor microenvironment
por: Sui, Hongshu, et al.
Publicado: (2022)

A transient receptor potential channel-related model based on machine learning for evaluating tumor microenvironment and immunotherapeutic strategies in acute myeloid leukemia
por: Hua, Jingsheng, et al.
Publicado: (2022)

Editorial: The role of tumor microenvironment in primary liver cancer therapeutic resistance
por: Pu, Zhangya, et al.
Publicado: (2022)

The extracellular microenvironment in immune dysregulation and inflammation in retinal disorders
por: Biasella, Fabiola, et al.
Publicado: (2023)

Cellular sources of dysregulated cytokines in relapsing-remitting multiple sclerosis
por: Romme Christensen, Jeppe, et al.
Publicado: (2012)

Myeleterosis in an ALPS5 patient with primary immune dysregulation syndrome
por: Long, Hongyu, et al.
Publicado: (2020)

Dysregulated plasma levels of miRNA-132 and miRNA-134 in patients with obsessive-compulsive disorder
por: Yue, Jihui, et al.
Publicado: (2020)

An unusual case of subacute combined degeneration due to nitrous oxide abuse, which relapsed after bariatric surgery: A case report
por: Chen, Wei, et al.
Publicado: (2022)

Stk10 Deficiency in Mice Promotes Tumor Growth by Dysregulating the Tumor Microenvironment
por: Ma, Jin-Xia, et al.
Publicado: (2022)

The tumour microenvironment links complement system dysregulation and hypoxic signalling
por: Olcina, Monica M, et al.
Publicado: (2019)

Trichostatin A reverses epithelial-mesenchymal transition and attenuates invasion and migration in MCF-7 breast cancer cells
por: Wang, Xiaoxiong, et al.
Publicado: (2020)

Dysregulation of innate cell types in the hepatic immune microenvironment of alcoholic liver cirrhosis
por: Ren, Ao, et al.
Publicado: (2023)

Association among prognostic nutritional index, post-operative infection and prognosis of stage II/III gastric cancer patients following radical gastrectomy
por: Xiao, Yanping, et al.
Publicado: (2022)

Targeting the Hepatic Microenvironment to Improve Ischemia/Reperfusion Injury: New Insights into the Immune and Metabolic Compartments
por: Gao, Fengqiang, et al.
Publicado: (2022)

Dysregulation of tumor microenvironment promotes malignant progression and predicts risk of metastasis in bladder cancer
por: Liu, Ji, et al.
Publicado: (2021)

The Mechanism Underlying the ncRNA Dysregulation Pattern in Hepatocellular Carcinoma and Its Tumor Microenvironment
por: Xue, Chen, et al.
Publicado: (2022)

Effects of Histone Deacetylase Inhibitor Panobinostat (LBH589) on Bone Marrow Mononuclear Cells of Relapsed or Refractory Multiple Myeloma Patients and Its Mechanisms
por: Ma, Yanping, et al.
Publicado: (2017)

Dysregulation of MiR-144-5p/RNF187 Axis Contributes To the Progression of Colorectal Cancer
por: Gao, Zhuo, et al.
Publicado: (2022)

Characteristics of the immunogenicity and tumor immune microenvironment in HER2-amplified lung adenocarcinoma
por: Wang, Qinyang, et al.
Publicado: (2022)

Two orders of magnitude enhancement in oxygen evolution reactivity on amorphous Ba(0.5)Sr(0.5)Co(0.8)Fe(0.2)O(3−δ) nanofilms with tunable oxidation state
por: Chen, Gao, et al.
Publicado: (2017)

Site-specific relapse pattern of the triple negative tumors in Chinese breast cancer patients
por: Lin, Yanping, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_3cis2lt3fsttah9dnc2ack32oo