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Gout in the thoracic spine causing acute paraplegia: illustrative case

BACKGROUND: Although spinal involvement by gout is not uncommon, spinal gout leading to symptomatic spinal cord compression in the thoracic spine is very rare and poses a diagnostic challenge by mimicking symptoms of more common diagnoses such as epidural abscess and malignancy. An even more unique...

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Detalles Bibliográficos
Autores principales: Koro, Lacin, Khanna, Ryan, Richards, Dominick, Karahalios, Dean G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neurological Surgeons 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265203/
https://www.ncbi.nlm.nih.gov/pubmed/35854950
http://dx.doi.org/10.3171/CASE21308
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author Koro, Lacin
Khanna, Ryan
Richards, Dominick
Karahalios, Dean G.
author_facet Koro, Lacin
Khanna, Ryan
Richards, Dominick
Karahalios, Dean G.
author_sort Koro, Lacin
collection PubMed
description BACKGROUND: Although spinal involvement by gout is not uncommon, spinal gout leading to symptomatic spinal cord compression in the thoracic spine is very rare and poses a diagnostic challenge by mimicking symptoms of more common diagnoses such as epidural abscess and malignancy. An even more unique presentation is spinal gout causing thoracic cord compression leading to acute paraplegia. OBSERVATIONS: The authors present an illustrative case of a 35-year-old man with thoracic spinal compression by tophaceous gout who developed rapid progression to complete paraplegia over a 5-day period. Magnetic resonance imaging of the thoracic spine revealed a cystic-appearing lesion within the dorsal extradural space of the lower thoracic spine extending from T8 to T10 accompanied by compression of the spinal cord. An emergent T9–10 laminectomy was performed, and the occupying lesion in the thoracic spine was resected. The diagnosis of spinal tophaceous gout was made by pathological examination. LESSONS: Although varying clinical manifestations of spinal gout have been reported in the literature, the patient’s age and the rapid progression to complete paraplegia over a 5-day period reveals a unique presentation that broadens understanding of the manner in which this condition can present and allow more rapid diagnosis and treatment.
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spelling pubmed-92652032022-07-18 Gout in the thoracic spine causing acute paraplegia: illustrative case Koro, Lacin Khanna, Ryan Richards, Dominick Karahalios, Dean G. J Neurosurg Case Lessons Case Lesson BACKGROUND: Although spinal involvement by gout is not uncommon, spinal gout leading to symptomatic spinal cord compression in the thoracic spine is very rare and poses a diagnostic challenge by mimicking symptoms of more common diagnoses such as epidural abscess and malignancy. An even more unique presentation is spinal gout causing thoracic cord compression leading to acute paraplegia. OBSERVATIONS: The authors present an illustrative case of a 35-year-old man with thoracic spinal compression by tophaceous gout who developed rapid progression to complete paraplegia over a 5-day period. Magnetic resonance imaging of the thoracic spine revealed a cystic-appearing lesion within the dorsal extradural space of the lower thoracic spine extending from T8 to T10 accompanied by compression of the spinal cord. An emergent T9–10 laminectomy was performed, and the occupying lesion in the thoracic spine was resected. The diagnosis of spinal tophaceous gout was made by pathological examination. LESSONS: Although varying clinical manifestations of spinal gout have been reported in the literature, the patient’s age and the rapid progression to complete paraplegia over a 5-day period reveals a unique presentation that broadens understanding of the manner in which this condition can present and allow more rapid diagnosis and treatment. American Association of Neurological Surgeons 2021-08-30 /pmc/articles/PMC9265203/ /pubmed/35854950 http://dx.doi.org/10.3171/CASE21308 Text en © 2021 The authors https://creativecommons.org/licenses/by-nc-nd/4.0/CC BY-NC-ND 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ).
spellingShingle Case Lesson
Koro, Lacin
Khanna, Ryan
Richards, Dominick
Karahalios, Dean G.
Gout in the thoracic spine causing acute paraplegia: illustrative case
title Gout in the thoracic spine causing acute paraplegia: illustrative case
title_full Gout in the thoracic spine causing acute paraplegia: illustrative case
title_fullStr Gout in the thoracic spine causing acute paraplegia: illustrative case
title_full_unstemmed Gout in the thoracic spine causing acute paraplegia: illustrative case
title_short Gout in the thoracic spine causing acute paraplegia: illustrative case
title_sort gout in the thoracic spine causing acute paraplegia: illustrative case
topic Case Lesson
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265203/
https://www.ncbi.nlm.nih.gov/pubmed/35854950
http://dx.doi.org/10.3171/CASE21308
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