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Case Report: The First Report on Moraxella canis Isolation From Corneal Ulcer in a Bulldog

A 5-year-old castrated male bulldog was diagnosed with a corneal ulcer accompanied by edema and conjunctival hyperemia. Ophthalmic examination and microbiological analysis were performed, and the bacteria were found to be gram-negative and globular. The isolated clone was identified as Moraxella can...

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Autores principales: Wang, Zhihao, Guo, Long, Li, Jun, Li, Jianji, Cui, Luying, Dong, Junsheng, Wang, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265251/
https://www.ncbi.nlm.nih.gov/pubmed/35812875
http://dx.doi.org/10.3389/fvets.2022.934081
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author Wang, Zhihao
Guo, Long
Li, Jun
Li, Jianji
Cui, Luying
Dong, Junsheng
Wang, Heng
author_facet Wang, Zhihao
Guo, Long
Li, Jun
Li, Jianji
Cui, Luying
Dong, Junsheng
Wang, Heng
author_sort Wang, Zhihao
collection PubMed
description A 5-year-old castrated male bulldog was diagnosed with a corneal ulcer accompanied by edema and conjunctival hyperemia. Ophthalmic examination and microbiological analysis were performed, and the bacteria were found to be gram-negative and globular. The isolated clone was identified as Moraxella canis (MZ579539) via MALDI-TOF MS and 16S rDNA sequencing. Antimicrobial susceptibility testing showed that the bacteria were sensitive to tetracycline and chloramphenicol, but resistant to levofloxacin and ciprofloxacin. After a conjunctival flap was placed, tobramycin ophthalmic solution and 5% sodium hyaluronate were administered. Following surgery, the ulcer was effectively controlled, and after 3 weeks, the cornea healed. This is the first case report of a canine corneal ulcer associated with M. canis, which should be considered when corneal ulceration or keratitis were suspected.
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spelling pubmed-92652512022-07-09 Case Report: The First Report on Moraxella canis Isolation From Corneal Ulcer in a Bulldog Wang, Zhihao Guo, Long Li, Jun Li, Jianji Cui, Luying Dong, Junsheng Wang, Heng Front Vet Sci Veterinary Science A 5-year-old castrated male bulldog was diagnosed with a corneal ulcer accompanied by edema and conjunctival hyperemia. Ophthalmic examination and microbiological analysis were performed, and the bacteria were found to be gram-negative and globular. The isolated clone was identified as Moraxella canis (MZ579539) via MALDI-TOF MS and 16S rDNA sequencing. Antimicrobial susceptibility testing showed that the bacteria were sensitive to tetracycline and chloramphenicol, but resistant to levofloxacin and ciprofloxacin. After a conjunctival flap was placed, tobramycin ophthalmic solution and 5% sodium hyaluronate were administered. Following surgery, the ulcer was effectively controlled, and after 3 weeks, the cornea healed. This is the first case report of a canine corneal ulcer associated with M. canis, which should be considered when corneal ulceration or keratitis were suspected. Frontiers Media S.A. 2022-06-24 /pmc/articles/PMC9265251/ /pubmed/35812875 http://dx.doi.org/10.3389/fvets.2022.934081 Text en Copyright © 2022 Wang, Guo, Li, Li, Cui, Dong and Wang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Wang, Zhihao
Guo, Long
Li, Jun
Li, Jianji
Cui, Luying
Dong, Junsheng
Wang, Heng
Case Report: The First Report on Moraxella canis Isolation From Corneal Ulcer in a Bulldog
title Case Report: The First Report on Moraxella canis Isolation From Corneal Ulcer in a Bulldog
title_full Case Report: The First Report on Moraxella canis Isolation From Corneal Ulcer in a Bulldog
title_fullStr Case Report: The First Report on Moraxella canis Isolation From Corneal Ulcer in a Bulldog
title_full_unstemmed Case Report: The First Report on Moraxella canis Isolation From Corneal Ulcer in a Bulldog
title_short Case Report: The First Report on Moraxella canis Isolation From Corneal Ulcer in a Bulldog
title_sort case report: the first report on moraxella canis isolation from corneal ulcer in a bulldog
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265251/
https://www.ncbi.nlm.nih.gov/pubmed/35812875
http://dx.doi.org/10.3389/fvets.2022.934081
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