Activation of Autophagic Flux Maintains Mitochondrial Homeostasis during Cardiac Ischemia/Reperfusion Injury

Reperfusion injury after extended ischemia accounts for approximately 50% of myocardial infarct size, and there is no standard therapy. HDAC inhibition reduces infarct size and enhances cardiomyocyte autophagy and PGC1α-mediated mitochondrial biogenesis when administered at the time of reperfusion....

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Detalles Bibliográficos
Autores principales: He, Lihao, Chu, Yuxin, Yang, Jing, He, Jin, Hua, Yutao, Chen, Yunxi, Benavides, Gloria, Rowe, Glenn C., Zhou, Lufang, Ballinger, Scott, Darley-Usmar, Victor, Young, Martin E., Prabhu, Sumanth D., Sethu, Palaniappan, Zhou, Yingling, Zhang, Cheng, Xie, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265292/
https://www.ncbi.nlm.nih.gov/pubmed/35805195
http://dx.doi.org/10.3390/cells11132111

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