HBV preS Mutations Promote Hepatocarcinogenesis by Inducing Endoplasmic Reticulum Stress and Upregulating Inflammatory Signaling

SIMPLE SUMMARY: Viral mutations at the preS region of hepatitis B virus (HBV) significantly increase the risk of developing hepatocellular carcinoma (HCC). Compared to HBV preS deletion, the oncogenic effect of preS combo mutation has rarely been investigated. With a cohort including 2114 subjects,...

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Detalles Bibliográficos
Autores principales: Liu, Wenbin, Cai, Shiliang, Pu, Rui, Li, Zixiong, Liu, Donghong, Zhou, Xinyu, Yin, Jianhua, Chen, Xi, Chen, Liping, Wu, Jianfeng, Tan, Xiaojie, Wang, Xin, Cao, Guangwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265300/
https://www.ncbi.nlm.nih.gov/pubmed/35805045
http://dx.doi.org/10.3390/cancers14133274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265300/
https://www.ncbi.nlm.nih.gov/pubmed/35805045
http://dx.doi.org/10.3390/cancers14133274

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