Mucosal Plasma Cell Activation and Proximity to Nerve Fibres Are Associated with Glycocalyx Reduction in Diarrhoea-Predominant Irritable Bowel Syndrome: Jejunal Barrier Alterations Underlying Clinical Manifestations

Irritable bowel syndrome (IBS) is a disorder of brain-gut interaction characterised by abdominal pain and changes in bowel habits. In the diarrhoea subtype (IBS-D), altered epithelial barrier and mucosal immune activation are associated with clinical manifestations. We aimed to further evaluate plas...

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Detalles Bibliográficos
Autores principales: Pardo-Camacho, Cristina, Ganda Mall, John-Peter, Martínez, Cristina, Pigrau, Marc, Expósito, Elba, Albert-Bayo, Mercé, Melón-Ardanaz, Elisa, Nieto, Adoración, Rodiño-Janeiro, Bruno, Fortea, Marina, Guagnozzi, Danila, Rodriguez-Urrutia, Amanda, de Torres, Inés, Santos-Briones, Ignacio, Azpiroz, Fernando, Lobo, Beatriz, Alonso-Cotoner, Carmen, Santos, Javier, González-Castro, Ana M., Vicario, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265332/
https://www.ncbi.nlm.nih.gov/pubmed/35805133
http://dx.doi.org/10.3390/cells11132046

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