Cargando…
Association of Sleep Duration with Hyperuricemia in Chinese Adults: A Prospective Longitudinal Study
Little is known about the association of sleep duration with hyperuricemia. Especially lacking is evidence from longitudinal studies. Based on the MJ Health Examination Database in Beijing, China, a prospective study was designed. Participants were classed into short, normal, and long groups by slee...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265381/ https://www.ncbi.nlm.nih.gov/pubmed/35805762 http://dx.doi.org/10.3390/ijerph19138105 |
_version_ | 1784743199670009856 |
---|---|
author | Yu, Huan Shi, Kexiang Yang, Haiming Sun, Dianjianyi Lv, Jun Ma, Yuan Man, Sailimai Yin, Jianchun Wang, Bo Yu, Canqing Li, Liming |
author_facet | Yu, Huan Shi, Kexiang Yang, Haiming Sun, Dianjianyi Lv, Jun Ma, Yuan Man, Sailimai Yin, Jianchun Wang, Bo Yu, Canqing Li, Liming |
author_sort | Yu, Huan |
collection | PubMed |
description | Little is known about the association of sleep duration with hyperuricemia. Especially lacking is evidence from longitudinal studies. Based on the MJ Health Examination Database in Beijing, China, a prospective study was designed. Participants were classed into short, normal, and long groups by sleep duration. The Cox regression model was used to estimate the hazard risk of hyperuricemia for short or long sleep duration compared with the normal group after adjusting for potential confounders. During a median 3.08 years follow-up, 4868 (14.31%) incident hyperuricemia events were documented among 34,025 participants with a crude incidence rate of 39.49 per 1000 persons. Years after adjusting for potential confounders, a 7% higher risk of hyperuricemia in the short sleep duration group (<7 h, 95% confidence interval: 1.01–1.14) and a 15% lower risk in the long sleep duration group (≥8 h, 95%CI: 0.74–0.97) were found compared with the normal group (7–8 h) (p for trend < 0.001). Nevertheless, the association of the short sleep duration group was marginally significant after further adjustment of the count of white blood cells (hazard ratio: 1.07, 95%CI: 1.00–1.13). Sleep duration was inversely associated with hyperuricemia, which highlights the public health significance of sufficient sleep duration for preventing hyperuricemia. |
format | Online Article Text |
id | pubmed-9265381 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92653812022-07-09 Association of Sleep Duration with Hyperuricemia in Chinese Adults: A Prospective Longitudinal Study Yu, Huan Shi, Kexiang Yang, Haiming Sun, Dianjianyi Lv, Jun Ma, Yuan Man, Sailimai Yin, Jianchun Wang, Bo Yu, Canqing Li, Liming Int J Environ Res Public Health Article Little is known about the association of sleep duration with hyperuricemia. Especially lacking is evidence from longitudinal studies. Based on the MJ Health Examination Database in Beijing, China, a prospective study was designed. Participants were classed into short, normal, and long groups by sleep duration. The Cox regression model was used to estimate the hazard risk of hyperuricemia for short or long sleep duration compared with the normal group after adjusting for potential confounders. During a median 3.08 years follow-up, 4868 (14.31%) incident hyperuricemia events were documented among 34,025 participants with a crude incidence rate of 39.49 per 1000 persons. Years after adjusting for potential confounders, a 7% higher risk of hyperuricemia in the short sleep duration group (<7 h, 95% confidence interval: 1.01–1.14) and a 15% lower risk in the long sleep duration group (≥8 h, 95%CI: 0.74–0.97) were found compared with the normal group (7–8 h) (p for trend < 0.001). Nevertheless, the association of the short sleep duration group was marginally significant after further adjustment of the count of white blood cells (hazard ratio: 1.07, 95%CI: 1.00–1.13). Sleep duration was inversely associated with hyperuricemia, which highlights the public health significance of sufficient sleep duration for preventing hyperuricemia. MDPI 2022-07-01 /pmc/articles/PMC9265381/ /pubmed/35805762 http://dx.doi.org/10.3390/ijerph19138105 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Yu, Huan Shi, Kexiang Yang, Haiming Sun, Dianjianyi Lv, Jun Ma, Yuan Man, Sailimai Yin, Jianchun Wang, Bo Yu, Canqing Li, Liming Association of Sleep Duration with Hyperuricemia in Chinese Adults: A Prospective Longitudinal Study |
title | Association of Sleep Duration with Hyperuricemia in Chinese Adults: A Prospective Longitudinal Study |
title_full | Association of Sleep Duration with Hyperuricemia in Chinese Adults: A Prospective Longitudinal Study |
title_fullStr | Association of Sleep Duration with Hyperuricemia in Chinese Adults: A Prospective Longitudinal Study |
title_full_unstemmed | Association of Sleep Duration with Hyperuricemia in Chinese Adults: A Prospective Longitudinal Study |
title_short | Association of Sleep Duration with Hyperuricemia in Chinese Adults: A Prospective Longitudinal Study |
title_sort | association of sleep duration with hyperuricemia in chinese adults: a prospective longitudinal study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265381/ https://www.ncbi.nlm.nih.gov/pubmed/35805762 http://dx.doi.org/10.3390/ijerph19138105 |
work_keys_str_mv | AT yuhuan associationofsleepdurationwithhyperuricemiainchineseadultsaprospectivelongitudinalstudy AT shikexiang associationofsleepdurationwithhyperuricemiainchineseadultsaprospectivelongitudinalstudy AT yanghaiming associationofsleepdurationwithhyperuricemiainchineseadultsaprospectivelongitudinalstudy AT sundianjianyi associationofsleepdurationwithhyperuricemiainchineseadultsaprospectivelongitudinalstudy AT lvjun associationofsleepdurationwithhyperuricemiainchineseadultsaprospectivelongitudinalstudy AT mayuan associationofsleepdurationwithhyperuricemiainchineseadultsaprospectivelongitudinalstudy AT mansailimai associationofsleepdurationwithhyperuricemiainchineseadultsaprospectivelongitudinalstudy AT yinjianchun associationofsleepdurationwithhyperuricemiainchineseadultsaprospectivelongitudinalstudy AT wangbo associationofsleepdurationwithhyperuricemiainchineseadultsaprospectivelongitudinalstudy AT yucanqing associationofsleepdurationwithhyperuricemiainchineseadultsaprospectivelongitudinalstudy AT liliming associationofsleepdurationwithhyperuricemiainchineseadultsaprospectivelongitudinalstudy |