Cargando…

Skeletal Muscle Pathogenesis in Polyglutamine Diseases

Polyglutamine diseases are characterized by selective dysfunction and degeneration of specific types of neurons in the central nervous system. In addition, nonneuronal cells can also be affected as a consequence of primary degeneration or due to neuronal dysfunction. Skeletal muscle is a primary sit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marchioretti, Caterina, Zuccaro, Emanuela, Pandey, Udai Bhan, Rosati, Jessica, Basso, Manuela, Pennuto, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265456/ https://www.ncbi.nlm.nih.gov/pubmed/35805189 http://dx.doi.org/10.3390/cells11132105

Ejemplares similares

Polyglutamine-Expanded Androgen Receptor Alteration of Skeletal Muscle Homeostasis and Myonuclear Aggregation Are Affected by Sex, Age and Muscle Metabolism
por: Chivet, Mathilde, et al.
Publicado: (2020)

Introduction to the Special Issue “Skeletal Muscle Atrophy: Mechanisms at a Cellular Level”
por: Zuccaro, Emanuela, et al.
Publicado: (2023)

MEF2 impairment underlies skeletal muscle atrophy in polyglutamine disease
por: Nath, Samir R., et al.
Publicado: (2020)

Antagonistic effect of cyclin-dependent kinases and a calcium-dependent phosphatase on polyglutamine-expanded androgen receptor toxic gain of function
por: Piol, Diana, et al.
Publicado: (2023)

Motor Neuron Diseases and Neuroprotective Peptides: A Closer Look to Neurons
por: Zuccaro, Emanuela, et al.
Publicado: (2021)

Protein Arginine Methyltransferase 6 Enhances Polyglutamine-Expanded Androgen Receptor Function and Toxicity in Spinal and Bulbar Muscular Atrophy
por: Scaramuzzino, Chiara, et al.
Publicado: (2015)

Post-translational Modifications and Protein Quality Control in Motor Neuron and Polyglutamine Diseases
por: Sambataro, Fabio, et al.
Publicado: (2017)

LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice
por: Prakasam, Ramachandran, et al.
Publicado: (2023)

Defective excitation-contraction coupling and mitochondrial respiration precede mitochondrial Ca(2+) accumulation in spinobulbar muscular atrophy skeletal muscle
por: Marchioretti, Caterina, et al.
Publicado: (2023)

On the role of RNA binding proteins in polyglutamine diseases: from pathogenesis to therapeutics
por: Conceição, André, et al.
Publicado: (2023)

Autophagy and polyglutamine diseases
por: Jimenez-Sanchez, Maria, et al.
Publicado: (2012)

Beyond motor neurons: expanding the clinical spectrum in Kennedy’s disease
por: Manzano, Raquel, et al.
Publicado: (2018)

Pathogenesis of Insulin Resistance in Skeletal Muscle
por: Abdul-Ghani, Muhammad A., et al.
Publicado: (2010)

Nuclear accumulation of polyglutamine disease proteins and neuropathology
por: Havel, Lauren S, et al.
Publicado: (2009)

Protein Arginine Methyltransferase 1 and 8 Interact with FUS to Modify Its Sub-Cellular Distribution and Toxicity In Vitro and In Vivo
por: Scaramuzzino, Chiara, et al.
Publicado: (2013)

Transcriptional Dysregulation and Post-translational Modifications in Polyglutamine Diseases: From Pathogenesis to Potential Therapeutic Strategies
por: Xiang, Chunchen, et al.
Publicado: (2018)

Editorial: Drosophila as a model to study neurodegenerative diseases
por: Liguori, Francesco, et al.
Publicado: (2023)

Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand
por: Ramesh, Nandini, et al.
Publicado: (2017)

Matrin-3 dysfunction in myopathy and motor neuron degeneration
por: Ward, Caroline, et al.
Publicado: (2021)

Advances in Modeling Polyglutamine Diseases Using Genome Editing Tools
por: Karwacka, Marianna, et al.
Publicado: (2022)

Protein Misfolding and Aggregation as a Therapeutic Target for Polyglutamine Diseases
por: Takeuchi, Toshihide, et al.
Publicado: (2017)

The emerging roles of long non‐coding RNAs in polyglutamine diseases
por: Dong, Xiaoyu, et al.
Publicado: (2021)

The Effect of Metabolites on Mitochondrial Functions in the Pathogenesis of Skeletal Muscle Aging
por: Gu, Xuchao, et al.
Publicado: (2022)

Editorial: The role of posttranslational modifications in polyglutamine diseases
por: Weber, Jonasz Jeremiasz, et al.
Publicado: (2023)

Polyglutamine Repeats in Viruses
por: Schein, Catherine H.
Publicado: (2018)

From Pathways to Targets: Understanding the Mechanisms behind Polyglutamine Disease
por: Weber, Jonasz Jeremiasz, et al.
Publicado: (2014)

Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization
por: Casci, Ian, et al.
Publicado: (2019)

Monomeric, Oligomeric and Polymeric Proteins in Huntington Disease and Other Diseases of Polyglutamine Expansion
por: Hoffner, Guylaine, et al.
Publicado: (2014)

Skeletal muscle laminin and MDC1A: pathogenesis and treatment strategies
por: Gawlik, Kinga I, et al.
Publicado: (2011)

Molecular Origin of Polyglutamine Aggregation in Neurodegenerative Diseases
por: Khare, Sagar D, et al.
Publicado: (2005)

Oligonucleotide-based strategies to combat polyglutamine diseases
por: Fiszer, Agnieszka, et al.
Publicado: (2014)

The Emerging Role of microRNAs in Polyglutamine Diseases
por: Dong, Xiaoyu, et al.
Publicado: (2019)

Polyglutamine diseases: looking beyond the neurodegenerative universe
por: Mielcarek, Michal, et al.
Publicado: (2020)

Genetics, Mechanisms, and Therapeutic Progress in Polyglutamine Spinocerebellar Ataxias
por: Buijsen, Ronald A.M., et al.
Publicado: (2019)

Functional implications of paralog genes in polyglutamine spinocerebellar ataxias
por: Felício, Daniela, et al.
Publicado: (2023)

Extracellular Vesicles Physiological Role and the Particular Case of Disease-Spreading Mechanisms in Polyglutamine Diseases
por: Moreira, Ricardo, et al.
Publicado: (2021)

An Exploration of the Universe of Polyglutamine Structures
por: Gómez-Sicilia, Àngel, et al.
Publicado: (2015)

Skeletal Muscle MicroRNAs as Key Players in the Pathogenesis of Amyotrophic Lateral Sclerosis
por: Di Pietro, Lorena, et al.
Publicado: (2018)

Praja1 ubiquitin ligase facilitates degradation of polyglutamine proteins and suppresses polyglutamine-mediated toxicity
por: Ghosh, Baijayanti, et al.
Publicado: (2021)

RNA toxicity in polyglutamine disorders: concepts, models, and progress of research
por: Fiszer, Agnieszka, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_hubavv7vel77urom4nle3au5mp