mGluR5 Is Substitutable for mGluR1 in Cerebellar Purkinje Cells for Motor Coordination, Developmental Synapse Elimination, and Motor Learning

Group I metabotropic glutamate receptors (mGluRs) include mGluR1 and mGluR5, which are coupled to the Gq family of heterotrimeric G-proteins and readily activated by their selective agonist 3,5-dihydroxyphenilglycine (DHPG). mGluR1 and mGluR5 exhibit nearly complementary distributions spatially or t...

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Detalles Bibliográficos
Autores principales: Harbers, Maria, Nakao, Harumi, Watanabe, Takaki, Matsuyama, Kyoko, Tohyama, Shoichi, Nakao, Kazuki, Kishimoto, Yasushi, Kano, Masanobu, Aiba, Atsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265771/
https://www.ncbi.nlm.nih.gov/pubmed/35805089
http://dx.doi.org/10.3390/cells11132004

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