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Insights into the Structure and Function of the Pex1/Pex6 AAA-ATPase in Peroxisome Homeostasis

The AAA-ATPases Pex1 and Pex6 are required for the formation and maintenance of peroxisomes, membrane-bound organelles that harbor enzymes for specialized metabolism. Together, Pex1 and Pex6 form a heterohexameric AAA-ATPase capable of unfolding substrate proteins via processive threading through a...

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Detalles Bibliográficos
Autores principales: Judy, Ryan M., Sheedy, Connor J., Gardner, Brooke M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265785/
https://www.ncbi.nlm.nih.gov/pubmed/35805150
http://dx.doi.org/10.3390/cells11132067

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