Evolutionary insight into the emergence of SARS-CoV-2 variants of concern

Analysis of SARS-CoV-2 evolution during chronic infection reveals that in this setting, the virus evolves to bear mutations similar to those seen in variants of concern, and that many of these mutations are associated with antibody evasion. However, as mutations associated with high SARS-CoV-2 trans...

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Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Research Briefing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266087/
https://www.ncbi.nlm.nih.gov/pubmed/35804153
http://dx.doi.org/10.1038/s41591-022-01892-2
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description Analysis of SARS-CoV-2 evolution during chronic infection reveals that in this setting, the virus evolves to bear mutations similar to those seen in variants of concern, and that many of these mutations are associated with antibody evasion. However, as mutations associated with high SARS-CoV-2 transmissibility are not observed, the emergence of variants of concern during chronic infection might be rare.
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spelling pubmed-92660872022-07-11 Evolutionary insight into the emergence of SARS-CoV-2 variants of concern Nat Med Research Briefing Analysis of SARS-CoV-2 evolution during chronic infection reveals that in this setting, the virus evolves to bear mutations similar to those seen in variants of concern, and that many of these mutations are associated with antibody evasion. However, as mutations associated with high SARS-CoV-2 transmissibility are not observed, the emergence of variants of concern during chronic infection might be rare. Nature Publishing Group US 2022-07-08 2022 /pmc/articles/PMC9266087/ /pubmed/35804153 http://dx.doi.org/10.1038/s41591-022-01892-2 Text en © Springer Nature America, Inc. 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Research Briefing
Evolutionary insight into the emergence of SARS-CoV-2 variants of concern
title Evolutionary insight into the emergence of SARS-CoV-2 variants of concern
title_full Evolutionary insight into the emergence of SARS-CoV-2 variants of concern
title_fullStr Evolutionary insight into the emergence of SARS-CoV-2 variants of concern
title_full_unstemmed Evolutionary insight into the emergence of SARS-CoV-2 variants of concern
title_short Evolutionary insight into the emergence of SARS-CoV-2 variants of concern
title_sort evolutionary insight into the emergence of sars-cov-2 variants of concern
topic Research Briefing
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266087/
https://www.ncbi.nlm.nih.gov/pubmed/35804153
http://dx.doi.org/10.1038/s41591-022-01892-2

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