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Cell–Fibronectin Interactions and Actomyosin Contractility Regulate the Segmentation Clock and Spatio-Temporal Somite Cleft Formation during Chick Embryo Somitogenesis
Fibronectin is essential for somite formation in the vertebrate embryo. Fibronectin matrix assembly starts as cells emerge from the primitive streak and ingress in the unsegmented presomitic mesoderm (PSM). PSM cells undergo cyclic waves of segmentation clock gene expression, followed by Notch-depen...
Autores principales: | Gomes de Almeida, Patrícia, Rifes, Pedro, Martins-Jesus, Ana P., Pinheiro, Gonçalo G., Andrade, Raquel P., Thorsteinsdóttir, Sólveig |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266262/ https://www.ncbi.nlm.nih.gov/pubmed/35805087 http://dx.doi.org/10.3390/cells11132003 |
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