Microglial Depletion Has No Impact on Disease Progression in a Mouse Model of Machado–Joseph Disease

Machado–Joseph disease (MJD), also known as spinocerebellar ataxia type 3 (SCA3), is an autosomal dominant neurodegenerative disorder (ND). While most research in NDs has been following a neuron-centric point of view, microglia are now recognized as crucial in the brain. Previous work revealed alter...

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Detalles Bibliográficos
Autores principales: Campos, Ana Bela, Duarte-Silva, Sara, Fernandes, Bruno, Coimbra, Bárbara, Campos, Jonas, Monteiro-Fernandes, Daniela, Teixeira-Castro, Andreia, Ambrósio, António Francisco, Maciel, Patrícia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266279/
https://www.ncbi.nlm.nih.gov/pubmed/35805106
http://dx.doi.org/10.3390/cells11132022

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