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Biochemical, Enzymatic, and Computational Characterization of Recurrent Somatic Mutations of the Human Protein Tyrosine Phosphatase PTP1B in Primary Mediastinal B Cell Lymphoma

Human protein tyrosine phosphatase 1B (PTP1B) is a ubiquitous non-receptor tyrosine phosphatase that serves as a major negative regulator of tyrosine phosphorylation cascades of metabolic and oncogenic importance such as the insulin, epidermal growth factor receptor (EGFR), and JAK/STAT pathways. In...

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Detalles Bibliográficos
Autores principales:	Liu, Rongxing, Sun, Yujie, Berthelet, Jérémy, Bui, Linh-Chi, Xu, Ximing, Viguier, Mireille, Dupret, Jean-Marie, Deshayes, Frédérique, Rodrigues Lima, Fernando
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266312/ https://www.ncbi.nlm.nih.gov/pubmed/35806064 http://dx.doi.org/10.3390/ijms23137060

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