5-Demethylnobiletin Inhibits Cell Proliferation, Downregulates ID1 Expression, Modulates the NF-κB/TNF-α Pathway and Exerts Antileukemic Effects in AML Cells

Acute myeloid leukemia (AML) is characterized by the dysregulation of hematopoietic cell proliferation, resulting in the accumulation of immature myeloid cells in bone marrow. 5-Demethylnobiletin (5-demethyl NOB), a citrus 5-hydroxylated polymethoxyflavone, has been reported to exhibit various bioac...

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Detalles Bibliográficos
Autores principales: Chen, Pei-Yi, Wang, Chih-Yang, Tsao, En-Ci, Chen, Yu-Ting, Wu, Ming-Jiuan, Ho, Chi-Tang, Yen, Jui-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266321/
https://www.ncbi.nlm.nih.gov/pubmed/35806401
http://dx.doi.org/10.3390/ijms23137392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266321/
https://www.ncbi.nlm.nih.gov/pubmed/35806401
http://dx.doi.org/10.3390/ijms23137392

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