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Theranostic Small-Molecule Prodrug Conjugates for Targeted Delivery and Controlled Release of Toll-like Receptor 7 Agonists
We previously reported the design and synthesis of a small-molecule drug conjugate (SMDC) platform that demonstrated several advantages over antibody–drug conjugates (ADCs) in terms of in vivo pharmacokinetics, solid tumor penetration, definitive chemical structure, and adaptability for modular synt...
Autores principales: | Debnath, Sashi, Hao, Guiyang, Guan, Bing, Thapa, Pawan, Hao, Justin, Hammers, Hans, Sun, Xiankai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266369/ https://www.ncbi.nlm.nih.gov/pubmed/35806163 http://dx.doi.org/10.3390/ijms23137160 |
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