Evidence for Dual Activation of I(K(M)) and I(K(Ca)) Caused by QO-58 (5-(2,6-Dichloro-5-fluoropyridin-3-yl)-3-phenyl-2-(trifluoromethyl)-1H-pyrazolol[1,5-a]pyrimidin-7-one)

QO-58 (5-(2,6-dichloro-5-fluoropyridin-3-yl)-3-phenyl-2-(trifluoromethyl)-1H-pyrazolol[1,5-a]pyrimidin-7-one) has been regarded to be an activator of K(V)7 channels with analgesic properties. However, whether and how the presence of this compound can result in any modifications of other types of mem...

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Detalles Bibliográficos
Autores principales: Wu, Chao-Liang, Fu, Poyuan, Cho, Hsin-Yen, Chuang, Tzu-Hsien, Wu, Sheng-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266432/
https://www.ncbi.nlm.nih.gov/pubmed/35806047
http://dx.doi.org/10.3390/ijms23137042

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