Cargando…
Genes Possessing the Most Frequent DNA DSBs Are Highly Associated with Development and Cancers, and Essentially Overlap with the rDNA-Contacting Genes
Double-strand DNA breakes (DSBs) are the most deleterious and widespread examples of DNA damage. They inevitably originate from endogenous mechanisms in the course of transcription, replication, and recombination, as well as from different exogenous factors. If not properly repaired, DSBs result in...
Autores principales: | Tchurikov, Nickolai A., Alembekov, Ildar R., Klushevskaya, Elena S., Kretova, Antonina N., Keremet, Ann M., Sidorova, Anastasia E., Meilakh, Polina B., Chechetkin, Vladimir R., Kravatskaya, Galina I., Kravatsky, Yuri V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266645/ https://www.ncbi.nlm.nih.gov/pubmed/35806206 http://dx.doi.org/10.3390/ijms23137201 |
Ejemplares similares
-
Fragments of rDNA Genes Scattered over the Human Genome Are Targets of Small RNAs
por: Tchurikov, Nickolai A., et al.
Publicado: (2022) -
Induction of the Erythroid Differentiation of K562 Cells Is Coupled with Changes in the Inter-Chromosomal Contacts of rDNA Clusters
por: Tchurikov, Nickolai A., et al.
Publicado: (2023) -
Chromosomal Translocations in NK-Cell Lymphomas Originate from Inter-Chromosomal Contacts of Active rDNA Clusters Possessing Hot Spots of DSBs
por: Tchurikov, Nickolai A., et al.
Publicado: (2021) -
Dynamics of Whole-Genome Contacts of Nucleoli in Drosophila Cells Suggests a Role for rDNA Genes in Global Epigenetic Regulation
por: Tchurikov, Nickolai A., et al.
Publicado: (2020) -
rDNA Clusters Make Contact with Genes that Are Involved in Differentiation and Cancer and Change Contacts after Heat Shock Treatment
por: Tchurikov, Nickolai A., et al.
Publicado: (2019)