RNA Cleavage Properties of Nucleobase-Specific RNase MC1 and Cusativin Are Determined by the Dinucleotide-Binding Interactions in the Enzyme-Active Site

Knowledge of the cleavage specificity of ribonucleases is critical for their application in RNA modification mapping or RNA-protein binding studies. Here, we detail the cleavage specificity and efficiency of ribonuclease MC1 and cusativin using a customized RNA sequence that contained all dinucleoti...

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Detalles Bibliográficos
Autores principales: Thakur, Priti, Atway, Jowad, Limbach, Patrick A., Addepalli, Balasubrahmanyam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266746/
https://www.ncbi.nlm.nih.gov/pubmed/35806025
http://dx.doi.org/10.3390/ijms23137021

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