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Advances in Membrane-Bound Catechol-O-Methyltransferase Stability Achieved Using a New Ionic Liquid-Based Storage Formulation

Membrane-bound catechol-O-methyltransferase (MBCOMT), present in the brain and involved in the main pathway of the catechol neurotransmitter deactivation, is linked to several types of human dementia, which are relevant pharmacological targets for new potent and nontoxic inhibitors that have been de...

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Detalles Bibliográficos
Autores principales: Gonçalves, Ana M., Sousa, Ângela, Pedro, Augusto Q., Romão, Maria J., Queiroz, João A., Gallardo, Eugénia, Passarinha, Luís A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266758/
https://www.ncbi.nlm.nih.gov/pubmed/35806268
http://dx.doi.org/10.3390/ijms23137264