Cargando…

Data-Driven Identification of Biomarkers for In Situ Monitoring of Drug Treatment in Bladder Cancer Organoids

Three-dimensional (3D) organoid culture recapitulating patient-specific histopathological and molecular diversity offers great promise for precision medicine in cancer. In this study, we established label-free imaging procedures, including Raman microspectroscopy (RMS) and fluorescence lifetime imag...

Descripción completa

Detalles Bibliográficos
Autores principales:	Becker, Lucas, Fischer, Felix, Fleck, Julia L., Harland, Niklas, Herkommer, Alois, Stenzl, Arnulf, Aicher, Wilhelm K., Schenke-Layland, Katja, Marzi, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266781/ https://www.ncbi.nlm.nih.gov/pubmed/35805961 http://dx.doi.org/10.3390/ijms23136956

Ejemplares similares

Effects of Scaffolds on Urine- and Urothelial Carcinoma Tissue-Derived Organoids from Bladder Cancer Patients
por: Walz, Simon, et al.
Publicado: (2023)

A Protocol for Organoids from the Urine of Bladder Cancer Patients
por: Walz, Simon, et al.
Publicado: (2023)

CD24: A Marker for an Extended Expansion Potential of Urothelial Cancer Cell Organoids In Vitro?
por: Geng, Ruizhi, et al.
Publicado: (2022)

Urinary Tract Tumor Organoids Reveal Eminent Differences in Drug Sensitivities When Compared to 2-Dimensional Culture Systems
por: Wei, Yi, et al.
Publicado: (2022)

Large Animal Models for Investigating Cell Therapies of Stress Urinary Incontinence
por: Amend, Bastian, et al.
Publicado: (2021)

Raman Imaging and Fluorescence Lifetime Imaging Microscopy for Diagnosis of Cancer State and Metabolic Monitoring
por: Becker, Lucas, et al.
Publicado: (2021)

Exploring the relationship between epigenetic DNA methylation and cardiac fibrosis through Raman microspectroscopy
por: Becker, Lucas, et al.
Publicado: (2023)

Stress Urinary Incontinence: An Unsolved Clinical Challenge
por: Harland, Niklas, et al.
Publicado: (2023)

Micro-Ultrasound: a way to bring imaging for prostate cancer back to urology
por: Harland, Niklas, et al.
Publicado: (2021)

Regulation of Immune Checkpoint Antigen CD276 (B7-H3) on Human Placenta-Derived Mesenchymal Stromal Cells in GMP-Compliant Cell Culture Media
por: Amend, Bastian, et al.
Publicado: (2023)

Role of Multiparametric Magnetic Resonance Imaging in Predicting Pathologic Outcomes in Prostate Cancer
por: Harland, Niklas, et al.
Publicado: (2021)

Elevated Expression of the Immune Checkpoint Ligand CD276 (B7-H3) in Urothelial Carcinoma Cell Lines Correlates Negatively with the Cell Proliferation
por: Harland, Niklas, et al.
Publicado: (2022)

Raman microspectroscopy and Raman imaging reveal biomarkers specific for thoracic aortic aneurysms
por: Sugiyama, Kaori, et al.
Publicado: (2021)

Monitoring the macrophage response towards biomaterial implants using label-free imaging
por: Lu, Chuan-en, et al.
Publicado: (2023)

Replacing Needle Injection by a Novel Waterjet Technology Grants Improved Muscle Cell Delivery in Target Tissues
por: Geng, Ruizhi, et al.
Publicado: (2022)

Raman Microspectroscopy Identifies Biochemical Activation Fingerprints in THP-1- and PBMC-Derived Macrophages
por: Feuerer, Nora, et al.
Publicado: (2022)

Marker-Independent Monitoring of in vitro and in vivo Degradation of Supramolecular Polymers Applied in Cardiovascular in situ Tissue Engineering
por: Marzi, Julia, et al.
Publicado: (2022)

Raman spectroscopy in biomedicine – non-invasive in vitro analysis of cells and extracellular matrix components in tissues
por: Brauchle, Eva, et al.
Publicado: (2013)

Prospects for regenerative medicine approaches in women's health
por: Schenke‐Layland, Katja, et al.
Publicado: (2015)

Injection of Porcine Adipose Tissue-Derived Stromal Cells by a Novel Waterjet Technology
por: Danalache, Marina, et al.
Publicado: (2021)

Laparoscopic Peritoneal Wash Cytology-Derived Primary Human Mesothelial Cells for In Vitro Cell Culture and Simulation of Human Peritoneum
por: Holl, Myriam, et al.
Publicado: (2021)

Prognostic relevance of positive urine markers in patients with negative cystoscopy during surveillance of bladder cancer
por: Todenhöfer, Tilman, et al.
Publicado: (2015)

A Peritoneal Purse-String Suture Prevents Symptomatic Lymphoceles in Retzius-Sparing Robot-Assisted Radical Prostatectomy
por: Harland, Niklas, et al.
Publicado: (2023)

Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform
por: Achberger, Kevin, et al.
Publicado: (2019)

Generation and Assessment of Functional Biomaterial Scaffolds for Applications in Cardiovascular Tissue Engineering and Regenerative Medicine
por: Hinderer, Svenja, et al.
Publicado: (2015)

Controlled Heterotypic Pseudo-Islet Assembly of Human β-Cells and Human Umbilical Vein Endothelial Cells Using Magnetic Levitation
por: Urbanczyk, Max, et al.
Publicado: (2020)

Lipidome profiling with Raman microspectroscopy identifies macrophage response to surface topographies of implant materials
por: Feuerer, Nora, et al.
Publicado: (2021)

WAT-on-a-chip integrating human mature white adipocytes for mechanistic research and pharmaceutical applications
por: Rogal, Julia, et al.
Publicado: (2020)

A Collagen-based Scaffold Delivering Exogenous MicroRNA-29B to Modulate Extracellular Matrix Remodeling
por: Monaghan, Michael, et al.
Publicado: (2014)

Autologous Human Immunocompetent White Adipose Tissue‐on‐Chip
por: Rogal, Julia, et al.
Publicado: (2022)

Treatment of Stress Urinary Incontinence with Muscle Stem Cells and Stem Cell Components: Chances, Challenges and Future Prospects
por: Schmid, Florian A., et al.
Publicado: (2021)

Cell death stages in single apoptotic and necrotic cells monitored by Raman microspectroscopy
por: Brauchle, Eva, et al.
Publicado: (2014)

Defining Oligometastatic Bladder Cancer: A Systematic Review
por: Bamias, Aristotelis, et al.
Publicado: (2023)

Cell Type-Specific Anti-Adhesion Properties of Peritoneal Cell Treatment with Plasma-Activated Media (PAM)
por: Holl, Myriam, et al.
Publicado: (2022)

A Rare Case of Synchronous Renal Cell Carcinoma of the Bladder Presenting With Gross Hematuria
por: Kruck, Stephan, et al.
Publicado: (2013)

Endocardial-to-mesenchymal transformation and mesenchymal cell colonization at the onset of human cardiac valve development
por: Monaghan, Michael G., et al.
Publicado: (2016)

Surface functionalization of electrospun scaffolds using recombinant human decorin attracts circulating endothelial progenitor cells
por: Hinderer, Svenja, et al.
Publicado: (2018)

Visualizing tropoelastin in a long-term human elastic fibre cell culture model
por: Halm, M., et al.
Publicado: (2016)

Enabling Multiphoton and Second Harmonic Generation Imaging in Paraffin-Embedded and Histologically Stained Sections
por: Monaghan, Michael G., et al.
Publicado: (2016)

Human heart-forming organoids recapitulate early heart and foregut development
por: Drakhlis, Lika, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_n9ofj2nmsag9gqo8m2ur2t1veb