The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen

INTRODUCTION: The aim of the study was to address the fatty acid (FA) status and its relationship with disease activity in patients with inflammatory bowel disease (IBD). METHODS: FA levels of the phospholipid fraction in serum and a colon biopsy specimen were measured in 17 patients with IBD. RESUL...

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Autores principales: Bugajska, Jolanta, Berska, Joanna, Zwolińska-Wcisło, Małgorzata, Sztefko, Krystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2022
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266795/
https://www.ncbi.nlm.nih.gov/pubmed/35832700
http://dx.doi.org/10.5114/aoms/150041
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author Bugajska, Jolanta
Berska, Joanna
Zwolińska-Wcisło, Małgorzata
Sztefko, Krystyna
author_facet Bugajska, Jolanta
Berska, Joanna
Zwolińska-Wcisło, Małgorzata
Sztefko, Krystyna
author_sort Bugajska, Jolanta
collection PubMed
description INTRODUCTION: The aim of the study was to address the fatty acid (FA) status and its relationship with disease activity in patients with inflammatory bowel disease (IBD). METHODS: FA levels of the phospholipid fraction in serum and a colon biopsy specimen were measured in 17 patients with IBD. RESULTS: A negative correlation between the histological activity of inflammation of the disease and the ratio of polyunsaturated FAs/no polyunsaturated FAs was observed. Moreover, the level of that ratio was lower in patients with IBDs as compared to controls. CONCLUSIONS: The FA profile in serum and in a colon biopsy specimen in patients with IBD is characteristic for essential fatty acid insufficiency.
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spelling pubmed-92667952022-07-12 The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen Bugajska, Jolanta Berska, Joanna Zwolińska-Wcisło, Małgorzata Sztefko, Krystyna Arch Med Sci Research Letter INTRODUCTION: The aim of the study was to address the fatty acid (FA) status and its relationship with disease activity in patients with inflammatory bowel disease (IBD). METHODS: FA levels of the phospholipid fraction in serum and a colon biopsy specimen were measured in 17 patients with IBD. RESULTS: A negative correlation between the histological activity of inflammation of the disease and the ratio of polyunsaturated FAs/no polyunsaturated FAs was observed. Moreover, the level of that ratio was lower in patients with IBDs as compared to controls. CONCLUSIONS: The FA profile in serum and in a colon biopsy specimen in patients with IBD is characteristic for essential fatty acid insufficiency. Termedia Publishing House 2022-06-03 /pmc/articles/PMC9266795/ /pubmed/35832700 http://dx.doi.org/10.5114/aoms/150041 Text en Copyright: © 2022 Termedia & Banach https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Research Letter
Bugajska, Jolanta
Berska, Joanna
Zwolińska-Wcisło, Małgorzata
Sztefko, Krystyna
The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen
title The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen
title_full The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen
title_fullStr The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen
title_full_unstemmed The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen
title_short The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen
title_sort risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266795/
https://www.ncbi.nlm.nih.gov/pubmed/35832700
http://dx.doi.org/10.5114/aoms/150041
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