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A Fully-Human Antibody Specifically Targeting a Membrane-Bound Fragment of CADM1 Potentiates the T Cell-Mediated Death of Human Small-Cell Lung Cancer Cells

Small-cell lung cancer (SCLC) is the most aggressive form of lung cancer and the leading cause of global cancer-related mortality. Despite the earlier identification of membrane-proximal cleavage of cell adhesion molecule 1 (CADM1) in cancers, the role of the membrane-bound fragment of CAMD1 (MF-CAD...

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Detalles Bibliográficos
Autores principales: Lee, Ji Hyun, Kim, Ji Woong, Yang, Ha Rim, Song, Seong-Won, Lee, Song-Jae, Jeon, Yeongha, Ju, Anna, Lee, Narim, Kim, Min-Gu, Kim, Minjoo, Hwang, Kyusang, Yoon, Jin Hwan, Shim, Hyunbo, Lee, Sukmook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266846/
https://www.ncbi.nlm.nih.gov/pubmed/35805896
http://dx.doi.org/10.3390/ijms23136895