Cargando…
Targeting the SREBP-1/Hsa-Mir-497/SCAP/FASN Oncometabolic Axis Inhibits the Cancer Stem-like and Chemoresistant Phenotype of Non-Small Cell Lung Carcinoma Cells
Background: Lung cancer remains a leading cause of cancer-related death, with an annual global mortality rate of 18.4%. Despite advances in diagnostic and therapeutic technologies, non–small cell lung carcinoma (NSCLC) continues to be characterized by a poor prognosis. This may be associated with th...
Autores principales: | Tiong, Tung-Yu, Weng, Pei-Wei, Wang, Chun-Hua, Setiawan, Syahru Agung, Yadav, Vijesh Kumar, Pikatan, Narpati Wesa, Fong, Iat-Hang, Yeh, Chi-Tai, Hsu, Chia-Hung, Kuo, Kuang-Tai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266857/ https://www.ncbi.nlm.nih.gov/pubmed/35806291 http://dx.doi.org/10.3390/ijms23137283 |
Ejemplares similares
-
Role of GDF15/MAPK14 Axis in Chondrocyte Senescence as a Novel Senomorphic Agent in Osteoarthritis
por: Weng, Pei-Wei, et al.
Publicado: (2022) -
Novel NFκB Inhibitor SC75741 Mitigates Chondrocyte Degradation and Prevents Activated Fibroblast Transformation by Modulating miR-21/GDF-5/SOX5 Signaling
por: Weng, Pei-Wei, et al.
Publicado: (2021) -
HNMT Upregulation Induces Cancer Stem Cell Formation and Confers Protection against Oxidative Stress through Interaction with HER2 in Non-Small-Cell Lung Cancer
por: Kuo, Kuang-Tai, et al.
Publicado: (2022) -
The E3 Ubiquitin Ligase NEDD4-1 Mediates Temozolomide-Resistant Glioblastoma through PTEN Attenuation and Redox Imbalance in Nrf2–HO-1 Axis
por: Chuang, Hao-Yu, et al.
Publicado: (2021) -
Tumor-Associated Macrophages Affect the Tumor Microenvironment and Radioresistance via the Upregulation of CXCL6/CXCR2 in Hepatocellular Carcinoma
por: Lee, Hsin-Lun, et al.
Publicado: (2023)