The Change in Paradigm for NSCLC Patients with EML4–ALK Translocation

The severe prognosis linked with a lung cancer diagnosis has changed with the discovery of oncogenic molecularly driven subgroups and the use of tailored treatment. ALK-translocated advanced lung cancer is the most interesting model, having achieved the longest overall survival. Here, we report the...

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Detalles Bibliográficos
Autores principales: Bearz, Alessandra, De Carlo, Elisa, Del Conte, Alessandro, Spina, Michele, Da Ros, Valentina, Bertoli, Elisa, Revelant, Alberto, Stanzione, Brigida, Tirelli, Umberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266866/
https://www.ncbi.nlm.nih.gov/pubmed/35806325
http://dx.doi.org/10.3390/ijms23137322
Descripción
Sumario:The severe prognosis linked with a lung cancer diagnosis has changed with the discovery of oncogenic molecularly driven subgroups and the use of tailored treatment. ALK-translocated advanced lung cancer is the most interesting model, having achieved the longest overall survival. Here, we report the most important paradigmatic shifts in the prognosis and treatment for this subgroup population occurred among lung cancer.

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