The Change in Paradigm for NSCLC Patients with EML4–ALK Translocation

The severe prognosis linked with a lung cancer diagnosis has changed with the discovery of oncogenic molecularly driven subgroups and the use of tailored treatment. ALK-translocated advanced lung cancer is the most interesting model, having achieved the longest overall survival. Here, we report the...

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Autores principales: Bearz, Alessandra, De Carlo, Elisa, Del Conte, Alessandro, Spina, Michele, Da Ros, Valentina, Bertoli, Elisa, Revelant, Alberto, Stanzione, Brigida, Tirelli, Umberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266866/
https://www.ncbi.nlm.nih.gov/pubmed/35806325
http://dx.doi.org/10.3390/ijms23137322
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author Bearz, Alessandra
De Carlo, Elisa
Del Conte, Alessandro
Spina, Michele
Da Ros, Valentina
Bertoli, Elisa
Revelant, Alberto
Stanzione, Brigida
Tirelli, Umberto
author_facet Bearz, Alessandra
De Carlo, Elisa
Del Conte, Alessandro
Spina, Michele
Da Ros, Valentina
Bertoli, Elisa
Revelant, Alberto
Stanzione, Brigida
Tirelli, Umberto
author_sort Bearz, Alessandra
collection PubMed
description The severe prognosis linked with a lung cancer diagnosis has changed with the discovery of oncogenic molecularly driven subgroups and the use of tailored treatment. ALK-translocated advanced lung cancer is the most interesting model, having achieved the longest overall survival. Here, we report the most important paradigmatic shifts in the prognosis and treatment for this subgroup population occurred among lung cancer.
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spelling pubmed-92668662022-07-09 The Change in Paradigm for NSCLC Patients with EML4–ALK Translocation Bearz, Alessandra De Carlo, Elisa Del Conte, Alessandro Spina, Michele Da Ros, Valentina Bertoli, Elisa Revelant, Alberto Stanzione, Brigida Tirelli, Umberto Int J Mol Sci Review The severe prognosis linked with a lung cancer diagnosis has changed with the discovery of oncogenic molecularly driven subgroups and the use of tailored treatment. ALK-translocated advanced lung cancer is the most interesting model, having achieved the longest overall survival. Here, we report the most important paradigmatic shifts in the prognosis and treatment for this subgroup population occurred among lung cancer. MDPI 2022-06-30 /pmc/articles/PMC9266866/ /pubmed/35806325 http://dx.doi.org/10.3390/ijms23137322 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bearz, Alessandra
De Carlo, Elisa
Del Conte, Alessandro
Spina, Michele
Da Ros, Valentina
Bertoli, Elisa
Revelant, Alberto
Stanzione, Brigida
Tirelli, Umberto
The Change in Paradigm for NSCLC Patients with EML4–ALK Translocation
title The Change in Paradigm for NSCLC Patients with EML4–ALK Translocation
title_full The Change in Paradigm for NSCLC Patients with EML4–ALK Translocation
title_fullStr The Change in Paradigm for NSCLC Patients with EML4–ALK Translocation
title_full_unstemmed The Change in Paradigm for NSCLC Patients with EML4–ALK Translocation
title_short The Change in Paradigm for NSCLC Patients with EML4–ALK Translocation
title_sort change in paradigm for nsclc patients with eml4–alk translocation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266866/
https://www.ncbi.nlm.nih.gov/pubmed/35806325
http://dx.doi.org/10.3390/ijms23137322
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