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Antimicrobial Properties of TiO(2) Microparticles Coated with Ca- and Cu-Based Composite Layers
The ability of TiO(2) to generate reactive oxygen species under UV radiation makes it an efficient candidate in antimicrobial studies. In this context, the preparation of TiO(2) microparticles coated with Ca- and Cu-based composite layers over which Cu(II), Cu(I), and Cu(0) species were identified i...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266884/ https://www.ncbi.nlm.nih.gov/pubmed/35805899 http://dx.doi.org/10.3390/ijms23136888 |
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author | Bucuresteanu, Razvan Ionita, Monica Chihaia, Viorel Ficai, Anton Trusca, Roxana-Doina Ilie, Cornelia-Ioana Kuncser, Andrei Holban, Alina-Maria Mihaescu, Grigore Petcu, Gabriela Nicolaev, Adela Costescu, Ruxandra M. Husch, Mihai Parvulescu, Viorica Ditu, Lia-Mara |
author_facet | Bucuresteanu, Razvan Ionita, Monica Chihaia, Viorel Ficai, Anton Trusca, Roxana-Doina Ilie, Cornelia-Ioana Kuncser, Andrei Holban, Alina-Maria Mihaescu, Grigore Petcu, Gabriela Nicolaev, Adela Costescu, Ruxandra M. Husch, Mihai Parvulescu, Viorica Ditu, Lia-Mara |
author_sort | Bucuresteanu, Razvan |
collection | PubMed |
description | The ability of TiO(2) to generate reactive oxygen species under UV radiation makes it an efficient candidate in antimicrobial studies. In this context, the preparation of TiO(2) microparticles coated with Ca- and Cu-based composite layers over which Cu(II), Cu(I), and Cu(0) species were identified is presented here. The obtained materials were characterized by a wide range of analytical methods, such as X-ray diffraction, electron microscopy (TEM, SEM), X-ray photoelectron (XPS), and UV-VIS spectroscopy. The antimicrobial efficiency was evaluated using qualitative and quantitative standard methods and standard clinical microbial strains. A significant aspect of this composite is that the antimicrobial properties were evidenced both in the presence and absence of the light, as result of competition between photo and electrical effects. However, the antibacterial effect was similar in darkness and light for all samples. Because no photocatalytic properties were found in the absence of copper, the results sustain the antibacterial effect of the electric field (generated by the electrostatic potential of the composite layer) both under the dark and in light conditions. In this way, the composite layers supported on the TiO(2) microparticles’ surface can offer continuous antibacterial protection and do not require the presence of a permanent light source for activation. However, the antimicrobial effect in the dark is more significant and is considered to be the result of the electric field effect generated on the composite layer. |
format | Online Article Text |
id | pubmed-9266884 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92668842022-07-09 Antimicrobial Properties of TiO(2) Microparticles Coated with Ca- and Cu-Based Composite Layers Bucuresteanu, Razvan Ionita, Monica Chihaia, Viorel Ficai, Anton Trusca, Roxana-Doina Ilie, Cornelia-Ioana Kuncser, Andrei Holban, Alina-Maria Mihaescu, Grigore Petcu, Gabriela Nicolaev, Adela Costescu, Ruxandra M. Husch, Mihai Parvulescu, Viorica Ditu, Lia-Mara Int J Mol Sci Article The ability of TiO(2) to generate reactive oxygen species under UV radiation makes it an efficient candidate in antimicrobial studies. In this context, the preparation of TiO(2) microparticles coated with Ca- and Cu-based composite layers over which Cu(II), Cu(I), and Cu(0) species were identified is presented here. The obtained materials were characterized by a wide range of analytical methods, such as X-ray diffraction, electron microscopy (TEM, SEM), X-ray photoelectron (XPS), and UV-VIS spectroscopy. The antimicrobial efficiency was evaluated using qualitative and quantitative standard methods and standard clinical microbial strains. A significant aspect of this composite is that the antimicrobial properties were evidenced both in the presence and absence of the light, as result of competition between photo and electrical effects. However, the antibacterial effect was similar in darkness and light for all samples. Because no photocatalytic properties were found in the absence of copper, the results sustain the antibacterial effect of the electric field (generated by the electrostatic potential of the composite layer) both under the dark and in light conditions. In this way, the composite layers supported on the TiO(2) microparticles’ surface can offer continuous antibacterial protection and do not require the presence of a permanent light source for activation. However, the antimicrobial effect in the dark is more significant and is considered to be the result of the electric field effect generated on the composite layer. MDPI 2022-06-21 /pmc/articles/PMC9266884/ /pubmed/35805899 http://dx.doi.org/10.3390/ijms23136888 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Bucuresteanu, Razvan Ionita, Monica Chihaia, Viorel Ficai, Anton Trusca, Roxana-Doina Ilie, Cornelia-Ioana Kuncser, Andrei Holban, Alina-Maria Mihaescu, Grigore Petcu, Gabriela Nicolaev, Adela Costescu, Ruxandra M. Husch, Mihai Parvulescu, Viorica Ditu, Lia-Mara Antimicrobial Properties of TiO(2) Microparticles Coated with Ca- and Cu-Based Composite Layers |
title | Antimicrobial Properties of TiO(2) Microparticles Coated with Ca- and Cu-Based Composite Layers |
title_full | Antimicrobial Properties of TiO(2) Microparticles Coated with Ca- and Cu-Based Composite Layers |
title_fullStr | Antimicrobial Properties of TiO(2) Microparticles Coated with Ca- and Cu-Based Composite Layers |
title_full_unstemmed | Antimicrobial Properties of TiO(2) Microparticles Coated with Ca- and Cu-Based Composite Layers |
title_short | Antimicrobial Properties of TiO(2) Microparticles Coated with Ca- and Cu-Based Composite Layers |
title_sort | antimicrobial properties of tio(2) microparticles coated with ca- and cu-based composite layers |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266884/ https://www.ncbi.nlm.nih.gov/pubmed/35805899 http://dx.doi.org/10.3390/ijms23136888 |
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