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Inhibition of Recruitment and Activation of Neutrophils by Pyridazinone-Scaffold-Based Compounds

In inflammatory diseases, polymorphonuclear neutrophils (PMNs) are known to produce elevated levels of pro-inflammatory cytokines and proteases. To limit ensuing exacerbated cell responses and tissue damage, novel therapeutic agents are sought. 4aa and 4ba, two pyridazinone-scaffold-based phosphodie...

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Detalles Bibliográficos
Autores principales:	Moniot, Aurélie, Braux, Julien, Siboni, Renaud, Guillaume, Christine, Audonnet, Sandra, Allart-Simon, Ingrid, Sapi, Janos, Tirouvanziam, Rabindra, Gérard, Stéphane, Gangloff, Sophie C., Velard, Frédéric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266889/ https://www.ncbi.nlm.nih.gov/pubmed/35806233 http://dx.doi.org/10.3390/ijms23137226

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