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MGMT and Whole-Genome DNA Methylation Impacts on Diagnosis, Prognosis and Therapy of Glioblastoma Multiforme

Epigenetic changes in DNA methylation contribute to the development of many diseases, including cancer. In glioblastoma multiforme, the most prevalent primary brain cancer and an incurable tumor with a median survival time of 15 months, a single epigenetic modification, the methylation of the O(6)-M...

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Detalles Bibliográficos
Autores principales: Della Monica, Rosa, Cuomo, Mariella, Buonaiuto, Michela, Costabile, Davide, Franca, Raduan Ahmed, Del Basso De Caro, Marialaura, Catapano, Giuseppe, Chiariotti, Lorenzo, Visconti, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266959/
https://www.ncbi.nlm.nih.gov/pubmed/35806153
http://dx.doi.org/10.3390/ijms23137148