Cargando…

MGMT and Whole-Genome DNA Methylation Impacts on Diagnosis, Prognosis and Therapy of Glioblastoma Multiforme

Epigenetic changes in DNA methylation contribute to the development of many diseases, including cancer. In glioblastoma multiforme, the most prevalent primary brain cancer and an incurable tumor with a median survival time of 15 months, a single epigenetic modification, the methylation of the O(6)-M...

Descripción completa

Detalles Bibliográficos
Autores principales:	Della Monica, Rosa, Cuomo, Mariella, Buonaiuto, Michela, Costabile, Davide, Franca, Raduan Ahmed, Del Basso De Caro, Marialaura, Catapano, Giuseppe, Chiariotti, Lorenzo, Visconti, Roberta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266959/ https://www.ncbi.nlm.nih.gov/pubmed/35806153 http://dx.doi.org/10.3390/ijms23137148

Ejemplares similares

A Rare Adult Primary Intracranial Sarcoma, DICER1-Mutant Identified by Epigenomic Profiling: A Case Report
por: Marinelli, Alfredo, et al.
Publicado: (2023)

Evaluation of MGMT Gene Methylation in Neuroendocrine Neoplasms
por: Della Monica, Rosa, et al.
Publicado: (2022)

Looking Beyond the Glioblastoma Mask: Is Genomics the Right Path?
por: Montella, Liliana, et al.
Publicado: (2022)

Targeted inhibition of the methyltransferase SETD8 synergizes with the Wee1 inhibitor adavosertib in restraining glioblastoma growth
por: Della Monica, Rosa, et al.
Publicado: (2023)

Epigenetic remodelling of Fxyd1 promoters in developing heart and brain tissues
por: Cuomo, Mariella, et al.
Publicado: (2022)

Methylome Profiling in Fabry Disease in Clinical Practice: A Proof of Concept
por: Di Risi, Teodolinda, et al.
Publicado: (2022)

Host fecal DNA specific methylation signatures mark gut dysbiosis and inflammation in children affected by autism spectrum disorder
por: Cuomo, Mariella, et al.
Publicado: (2023)

Ultra-Deep DNA Methylation Analysis of X-Linked Genes: GLA and AR as Model Genes
por: De Riso, Giulia, et al.
Publicado: (2020)

Brain Gliomas and Ollier Disease: Molecular Findings as Predictive Risk Factors?
por: Corvino, Sergio, et al.
Publicado: (2022)

The Role of miRNA for the Treatment of MGMT Unmethylated Glioblastoma Multiforme
por: Kirstein, Anna, et al.
Publicado: (2020)

Lomeguatrib Increases the Radiosensitivity of MGMT Unmethylated Human Glioblastoma Multiforme Cell Lines
por: Kirstein, Anna, et al.
Publicado: (2021)

N6-Isopentenyladenosine Impairs Mitochondrial Metabolism through Inhibition of EGFR Translocation on Mitochondria in Glioblastoma Cells
por: Pagano, Cristina, et al.
Publicado: (2022)

Fast routine assessment of MGMT promoter methylation
por: Hench, Ivana Bratic, et al.
Publicado: (2020)

Extra-Neural Metastases of Late Recurrent Myxopapillary Ependymoma to Left Lumbar Paravertebral Muscles: Case Report and Review of the Literature
por: Mastantuoni, Ciro, et al.
Publicado: (2022)

Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme
por: Oberstadt, Moritz C, et al.
Publicado: (2013)

The Impact of O6-Methylguanine-DNA Methyltransferase (MGMT) Promoter Methylation on the Outcomes of Patients with Leiomyosarcoma Treated with Dacarbazine
por: Cannella, Lucia, et al.
Publicado: (2023)

Atypical Teratoid Rhabdoid Tumor: A Possible Oriented Female Pathology?
por: Baiano, Cinzia, et al.
Publicado: (2022)

Up-regulation of miR-370-3p restores glioblastoma multiforme sensitivity to temozolomide by influencing MGMT expression
por: Gao, Yong-tao, et al.
Publicado: (2016)

Spinal cervical extradural hemangioblastoma
por: Mariniello, Giuseppe, et al.
Publicado: (2022)

Association between MGMT Enhancer Methylation and MGMT Promoter Methylation, MGMT Protein Expression, and Overall Survival in Glioblastoma
por: Zappe, Katja, et al.
Publicado: (2023)

Interventional cytopathologist can successfully combine ultrasonographical and microscopic skills to narrow the differential diagnosis in fine needle aspiration of neck paraganglioma
por: Carillo, Anna Maria, et al.
Publicado: (2022)

Glioblastoma Multiforme
por: Sheehan, Jonas M., et al.
Publicado: (2012)

A ”Clickable” Probe for Active MGMT in Glioblastoma Demonstrates Two Discrete Populations of MGMT
por: Raghavan, Sudhir, et al.
Publicado: (2020)

Neoplasms and tumor-like lesions of the sellar region: imaging findings with correlation to pathology and 2021 WHO classification
por: Ugga, Lorenzo, et al.
Publicado: (2023)

MGMT promoter methylation in Peruvian patients with glioblastoma
por: Belmar-Lopez, Carolina, et al.
Publicado: (2018)

BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1α stability and MGMT expression
por: Persano, L, et al.
Publicado: (2012)

Glioblastoma multiforme – an overview
por: Urbańska, Kaja, et al.
Publicado: (2014)

Incidentalomas to glioblastoma multiforme
por: Sachdev, Bobby, et al.
Publicado: (2014)

Whole-Genome Multi-omic Study of Survival in Patients with Glioblastoma Multiforme
por: Bernal Rubio, Yeni L., et al.
Publicado: (2018)

Volumetric and MGMT parameters in glioblastoma patients: Survival analysis
por: Iliadis, Georgios, et al.
Publicado: (2012)

MGMT Methylation Status: The Advent of Stratified Therapy in Glioblastoma?
por: Hau, Peter, et al.
Publicado: (2007)

Advances in the management of glioblastoma: the role of temozolomide and MGMT testing
por: Thomas, Reena P, et al.
Publicado: (2012)

Veliparib in combination with radiotherapy for the treatment of MGMT unmethylated glioblastoma
por: Jue, Toni Rose, et al.
Publicado: (2017)

The MGMT promoter single-nucleotide polymorphism rs1625649 had prognostic impact on patients with MGMT methylated glioblastoma
por: Hsu, Chih-Yi, et al.
Publicado: (2017)

Bortezomib administered prior to temozolomide depletes MGMT, chemosensitizes glioblastoma with unmethylated MGMT promoter and prolongs animal survival
por: Rahman, Mohummad Aminur, et al.
Publicado: (2019)

DNA methylation impact on Fabry disease
por: Di Risi, Teodolinda, et al.
Publicado: (2021)

Tectal plate glioblastoma multiforme
por: Nemer, Michael D., et al.
Publicado: (2011)

Bilateral cystic glioblastoma multiforme
por: Kumar, Sushil, et al.
Publicado: (2013)

Glioblastoma Multiforme Stem Cells
por: Dimov, Irena, et al.
Publicado: (2011)

Atypical Presentation of Glioblastoma Multiforme
por: Al-Janabi, Wissam, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_7qc7bp0p2tq1df4q6t3i0u7n80