Cargando…

Gene Mutational Clusters in the Tumors of Colorectal Cancer Patients With a Family History of Cancer

INTRODUCTION: Family history is a high-risk factor for colorectal cancer (CRC). The risk comes not only from known germline mutations but also from the other family-related mechanisms. Uncovering them would be an important step to improve the diagnosis and treatment of these patients. METHOD: Sample...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, He, Deng, Ting, Guo, Yuntong, Chen, Hao, Cui, Xiaolong, Duan, Jingjing, Yang, Yuchong, Guo, Zhixin, Ba, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266985/ https://www.ncbi.nlm.nih.gov/pubmed/35814400 http://dx.doi.org/10.3389/fonc.2022.814397

Ejemplares similares

The Natural History of pT1 Colorectal Cancer
por: Risio, Mauro
Publicado: (2012)

Colorectal Cancer: Molecular Mutations and Polymorphisms
por: Sameer, Aga Syed
Publicado: (2013)

Efficacy and survival of anti-PD-1 antibody in combination with trastuzumab and chemotherapy versus trastuzumab and chemotherapy as first-line treatment of HER2-positive metastasis gastric adenocarcinoma: a retrospective study
por: Deng, Ting, et al.
Publicado: (2023)

HK2 Is a Crucial Downstream Regulator of miR-148a for the Maintenance of Sphere-Forming Property and Cisplatin Resistance in Cervical Cancer Cells
por: Yang, Hao, et al.
Publicado: (2021)

LncRNA OTUD6B-AS1 Induces Cisplatin Resistance in Cervical Cancer Cells Through Up-Regulating Cyclin D2 via miR-206
por: Hou, Hui, et al.
Publicado: (2021)

The optimal time of starting adjuvant chemotherapy after curative surgery in patients with colorectal cancer
por: Yang, Yuchong, et al.
Publicado: (2023)

Third-line treatment patterns and clinical outcomes for metastatic colorectal cancer: a retrospective real-world study
por: Deng, Ting, et al.
Publicado: (2023)

Family History of Cancer in Benign Brain Tumor Subtypes Versus Gliomas
por: Ostrom, Quinn T., et al.
Publicado: (2012)

Incidence of Pathogenic Variants in Those With a Family History of Pancreatic Cancer
por: Macklin, Sarah K., et al.
Publicado: (2018)

Family History and Risk of Upper Gastrointestinal Cancer in the Linxian General Population
por: Yang, Huan, et al.
Publicado: (2021)

Cancer screening and breast cancer family history in Spanish-speaking Hispanic/Latina women in California
por: Tamayo, Lizeth I., et al.
Publicado: (2022)

Cancer screening and breast cancer family history in Spanish-speaking Hispanic/Latina women in California
por: Tamayo, Lizeth I., et al.
Publicado: (2023)

Mutation Spectrum of Cancer-Associated Genes in Patients With Early Onset of Colorectal Cancer
por: Zhunussova, Gulnur, et al.
Publicado: (2019)

Comparison Between Familial Colorectal Cancer Type X and Lynch Syndrome: Molecular, Clinical, and Pathological Characteristics and Pedigrees
por: Xu, Yun, et al.
Publicado: (2020)

Risks of cancers for carriers of monoallelic MUTYH mutation with a family history of colorectal cancer
por: Win, Aung K, et al.
Publicado: (2011)

Biological Roles and Therapeutic Applications of IDH2 Mutations in Human Cancer
por: Guo, Jinxiu, et al.
Publicado: (2021)

Clinicopathologic Features and Prognosis of BRAF Mutated Colorectal Cancer Patients
por: Guan, Wen-Long, et al.
Publicado: (2020)

Crosstalk Between DNA Methylation and Gene Mutations in Colorectal Cancer
por: Dobre, Maria, et al.
Publicado: (2021)

Development and validation of a prognostic 9-gene signature for colorectal cancer
por: Cui, Junpeng, et al.
Publicado: (2022)

Family history of colorectal cancer in Iran
por: Mahdavinia, Mahboobeh, et al.
Publicado: (2005)

High tumor mutation burden indicates better prognosis in colorectal cancer patients with KRAS mutations
por: Wang, Jianlei, et al.
Publicado: (2022)

Mutations matter: An observational study of the prognostic and predictive value of KRAS mutations in metastatic colorectal cancer
por: Lavacchi, Daniele, et al.
Publicado: (2022)

Perspectives in the Treatment of RAS or BRAF Mutated Metastatic Colorectal Cancer Patients
por: Rosati, Gerardo, et al.
Publicado: (2021)

Statin Treatment as a Targeted Therapy for APC-Mutated Colorectal Cancer
por: Shailes, Hannah, et al.
Publicado: (2022)

Recurrent Somatic MAP2K1 Mutations in Papillary Thyroid Cancer and Colorectal Cancer
por: Bu, Rong, et al.
Publicado: (2021)

Efficacy and safety of acupuncture-point stimulation combined with opioids for the treatment of moderate to severe cancer pain: a network meta-analysis of randomized controlled trials
por: Zhang, Qinglin, et al.
Publicado: (2023)

Association of Family History of Type 2 Diabetes with Prostate Cancer: A National Cohort Study
por: Ji, Jianguang, et al.
Publicado: (2016)

Comprehensive Analysis of Role of Cyclin-Dependent Kinases Family Members in Colorectal Cancer
por: Guan, Liping, et al.
Publicado: (2022)

Role and therapeutic potential of DEAD-box RNA helicase family in colorectal cancer
por: Zheng, Bichun, et al.
Publicado: (2023)

Family history of cancer and risk of colorectal cancer in Italy.
por: Negri, E., et al.
Publicado: (1998)

MicroRNAs Expression Patterns Predict Tumor Mutational Burden in Colorectal Cancer
por: Huang, Jiahao, et al.
Publicado: (2021)

Case Report: Coinheritance of Germline Mutations in APC and BRCA1 in Colorectal Cancer
por: Huang, Wei, et al.
Publicado: (2021)

Editorial: The Treatment of RAS or BRAF Mutated Metastatic Colorectal Cancer: Challenges and Perspectives
por: Ottaiano, Alessandro, et al.
Publicado: (2022)

Comprehensive characterization of FBXW7 mutational and clinicopathological profiles in human colorectal cancers
por: Liu, Yiping, et al.
Publicado: (2023)

Prognostic and therapeutic impact of the KRAS G12C mutation in colorectal cancer
por: Qunaj, Lindor, et al.
Publicado: (2023)

Serum Chemokine CXCL7 as a Diagnostic Biomarker for Colorectal Cancer
por: Li, Longhai, et al.
Publicado: (2019)

The Leptin Gene Family and Colorectal Cancer: Interaction with Smoking Behavior and Family History of Cancer
por: Liu, Li, et al.
Publicado: (2013)

Development and validation of a web-based predictive model for preoperative diagnosis of localized colorectal cancer and colorectal adenoma
por: Lu, Yan, et al.
Publicado: (2023)

Unique Profile of Driver Gene Mutations in Patients With Non-Small-Cell Lung Cancer in Qujing City, Yunnan Province, Southwest China
por: Zhou, Yongchun, et al.
Publicado: (2021)

Comprehensive Analysis of Prognostic Value and Immune Infiltration of Chromobox Family Members in Colorectal Cancer
por: Li, Qingshang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_eo3bjg35redlafj282qvdrmp8j