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Revisiting the Function of p21(CDKN1A) in DNA Repair: The Influence of Protein Interactions and Stability
The p21(CDKN1A) protein is an important player in the maintenance of genome stability through its function as a cyclin-dependent kinase inhibitor, leading to cell-cycle arrest after genotoxic damage. In the DNA damage response, p21 interacts with specific proteins to integrate cell-cycle arrest with...
Autores principales: | Ticli, Giulio, Cazzalini, Ornella, Stivala, Lucia A., Prosperi, Ennio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267019/ https://www.ncbi.nlm.nih.gov/pubmed/35806061 http://dx.doi.org/10.3390/ijms23137058 |
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