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A New Bistable Switch Model of Alzheimer’s Disease Pathogenesis

We propose a model to explain the pathogenesis of Alzheimer’s disease (AD) based on the theory that any disease affecting a healthy organism originates from a bistable feedback loop that shifts the system from a physiological to a pathological condition. We focused on the known double inhibitory loo...

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Detalles Bibliográficos
Autores principales: Burlando, Bruno, Losacco, Serena, Villa, Viviana, Fedele, Ernesto, Ricciarelli, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267076/
https://www.ncbi.nlm.nih.gov/pubmed/35806088
http://dx.doi.org/10.3390/ijms23137061

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