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A New Bistable Switch Model of Alzheimer’s Disease Pathogenesis
We propose a model to explain the pathogenesis of Alzheimer’s disease (AD) based on the theory that any disease affecting a healthy organism originates from a bistable feedback loop that shifts the system from a physiological to a pathological condition. We focused on the known double inhibitory loo...
Autores principales: | Burlando, Bruno, Losacco, Serena, Villa, Viviana, Fedele, Ernesto, Ricciarelli, Roberta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267076/ https://www.ncbi.nlm.nih.gov/pubmed/35806088 http://dx.doi.org/10.3390/ijms23137061 |
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