Effects of PCSK-9 Inhibition by Alirocumab Treatments on Biliary Cirrhotic Rats

Hyperlipidemia and oxidative stress with elevated oxidized low-density lipoprotein (ox-LDL) exacerbate hepatic inflammation and fibrosis. The plasma level of low-density lipoprotein (LDL) is controlled by proprotein convertase subtilisin/kexin 9 (PCSK9). Alirocumab is a monoclonal antibody that decr...

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Detalles Bibliográficos
Autores principales: Huang, Hui-Chun, Hsu, Shao-Jung, Chang, Ching-Chih, Chuang, Chiao-Lin, Hou, Ming-Chih, Lee, Fa-Yauh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267099/
https://www.ncbi.nlm.nih.gov/pubmed/35806383
http://dx.doi.org/10.3390/ijms23137378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267099/
https://www.ncbi.nlm.nih.gov/pubmed/35806383
http://dx.doi.org/10.3390/ijms23137378

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