Cargando…

Methuosis Contributes to Jaspine-B-Induced Cell Death

Methuosis is a type of programmed cell death in which the cytoplasm is occupied by fluid-filled vacuoles that originate from macropinosomes (cytoplasmic vacuolation). A few molecules have been reported to behave as methuosis inducers in cancer cell lines. Jaspine B (JB) is a natural anhydrous sphing...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bielsa, Núria, Casasampere, Mireia, Abad, Jose Luis, Enrich, Carlos, Delgado, Antonio, Fabriàs, Gemma, Lizcano, Jose M., Casas, Josefina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267113/ https://www.ncbi.nlm.nih.gov/pubmed/35806262 http://dx.doi.org/10.3390/ijms23137257

Ejemplares similares

Click and count: specific detection of acid ceramidase activity in live cells
por: Casasampere, Mireia, et al.
Publicado: (2020)

Pharmacokinetics of Jaspine B and Enhancement of Intestinal Absorption of Jaspine B in the Presence of Bile Acid in Rats
por: Choi, Min-Koo, et al.
Publicado: (2017)

High-throughput discovery of novel small-molecule inhibitors of acid Ceramidase
por: Aseeri, Mazen, et al.
Publicado: (2022)

Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulation
por: Torres, Sandra, et al.
Publicado: (2021)

From Pinocytosis to Methuosis—Fluid Consumption as a Risk Factor for Cell Death
por: Ritter, Markus, et al.
Publicado: (2021)

Indolyl-Pyridinyl-Propenone-Induced Methuosis through the Inhibition of PIKFYVE
por: Cho, Hyelim, et al.
Publicado: (2018)

Stereodivergent synthesis of jaspine B and its isomers using a carbohydrate-derived alkoxyallene as C(3)-building block
por: Schmiedel, Volker Martin, et al.
Publicado: (2013)

Correction to Indolyl-Pyridinyl-Propenone-Induced Methuosis through the Inhibition of PIKFYVE
por: Cho, Hyelim, et al.
Publicado: (2018)

Assessments of iodoindoles and abamectin as inducers of methuosis in pinewood nematode, Bursaphelenchus xylophilus
por: Rajasekharan, Satish Kumar, et al.
Publicado: (2017)

Diets with Higher ω-6/ω-3 Ratios Show Differences in Ceramides and Fatty Acid Levels Accompanied by Increased Amyloid-Beta in the Brains of Male APP/PS1 Transgenic Mice
por: Ordóñez-Gutiérrez, Lara, et al.
Publicado: (2021)

The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma
por: Li, Zehui, et al.
Publicado: (2019)

Formulation, Characterization, and In Vitro/In Vivo Efficacy Studies of a Novel Liposomal Drug Delivery System of Amphiphilic Jaspine B for Treatment of Synovial Sarcoma
por: Khajeh pour, Sana, et al.
Publicado: (2022)

A chalcone-related small molecule that induces methuosis, a novel form of non-apoptotic cell death, in glioblastoma cells
por: Overmeyer, Jean H, et al.
Publicado: (2011)

CK2 inhibition with silmitasertib promotes methuosis-like cell death associated to catastrophic massive vacuolization of colorectal cancer cells
por: Silva-Pavez, Eduardo, et al.
Publicado: (2019)

Ionizing radiation results in a mixture of cellular outcomes including mitotic catastrophe, senescence, methuosis, and iron-dependent cell death
por: Adjemian, Sandy, et al.
Publicado: (2020)

Synthesis and Biological Evaluation of Indolyl-Pyridinyl-Propenones Having Either Methuosis or Microtubule Disruption Activity
por: Trabbic, Christopher J., et al.
Publicado: (2015)

CX-4945 Induces Methuosis in Cholangiocarcinoma Cell Lines by a CK2-Independent Mechanism
por: Lertsuwan, Jomnarong, et al.
Publicado: (2018)

The Dual Role of Macropinocytosis in Cancers: Promoting Growth and Inducing Methuosis to Participate in Anticancer Therapies as Targets
por: Song, Shaojuan, et al.
Publicado: (2021)

Tubeimoside-2 Triggers Methuosis in Hepatocarcinoma Cells through the MKK4–p38α Axis
por: Gan, Yichao, et al.
Publicado: (2023)

Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease
por: Torres, Sandra, et al.
Publicado: (2016)

Fluorescently Labeled Ceramides and 1-Deoxyceramides: Synthesis, Characterization, and Cellular Distribution Studies
por: Izquierdo, Eduardo, et al.
Publicado: (2022)

Ethanol Extract of the Infructescence of Platycarya strobilacea Sieb. et Zucc. Induces Methuosis of Human Nasopharyngeal Carcinoma Cells
por: Liu, Jinkun, et al.
Publicado: (2020)

A lovastatin-elicited genetic program inhibits M2 macrophage polarization and enhances T cell infiltration into spontaneous mouse mammary tumors
por: Mira, Emilia, et al.
Publicado: (2013)

CD99 triggering induces methuosis of Ewing sarcoma cells through IGF-1R/RAS/Rac1 signaling
por: Manara, Maria Cristina, et al.
Publicado: (2016)

Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis
por: Martínez, Laura, et al.
Publicado: (2015)

Plasmalogen enrichment in exosomes secreted by a nematode parasite versus those derived from its mouse host: implications for exosome stability and biology
por: Simbari, Fabio, et al.
Publicado: (2016)

Pharmacological Elevation of Cellular Dihydrosphingomyelin Provides a Novel Antiviral Strategy against West Nile Virus Infection
por: Jiménez de Oya, Nereida, et al.
Publicado: (2023)

Obesogens beyond Vertebrates: Lipid Perturbation by Tributyltin in the Crustacean Daphnia magna
por: Jordão, Rita, et al.
Publicado: (2015)

Ovarian Hormone-Dependent Effects of Dietary Lipids on APP/PS1 Mouse Brain
por: Herrera, Jose Luis, et al.
Publicado: (2019)

Ovarian Function Modulates the Effects of Long-Chain Polyunsaturated Fatty Acids on the Mouse Cerebral Cortex
por: Herrera, Jose L., et al.
Publicado: (2018)

Sialyllactose in Viral Membrane Gangliosides Is a Novel Molecular Recognition Pattern for Mature Dendritic Cell Capture of HIV-1
por: Izquierdo-Useros, Nuria, et al.
Publicado: (2012)

Cholesterol in the Viral Membrane is a Molecular Switch Governing HIV‐1 Env Clustering
por: Nieto‐Garai, Jon Ander, et al.
Publicado: (2020)

Ghrelin Causes a Decline in GABA Release by Reducing Fatty Acid Oxidation in Cortex
por: Mir, Joan Francesc, et al.
Publicado: (2018)

Correction: Lertsuwan et al. CX-4945 Induces Methuosis in Cholangiocarcinoma Cell Lines by a CK2-Independent Mechanism. Cancers 2018, 10, 283
por: Lertsuwan, Jomnarong, et al.
Publicado: (2022)

Anti-c-MET Fab-Grb2-Gab1 Fusion Protein-Mediated Interference of c-MET Signaling Pathway Induces Methuosis in Tumor Cells
por: Dou, Xiaoqian, et al.
Publicado: (2022)

Corrigendum to “Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulation” [Redox Biol. 2021 45 102052]
por: Torres, S., et al.
Publicado: (2022)

CELLULAR CHANGES THAT ACCOMPANY SHEDDING OF HUMAN CORNEOCYTES
por: Lin, Tzu-Kai, et al.
Publicado: (2012)

On-Tissue Localization of Ceramides and Other Sphingolipids by MALDI Mass Spectrometry Imaging
por: Jones, E. Ellen, et al.
Publicado: (2014)

Long-Term Increased Carnitine Palmitoyltransferase 1A Expression in Ventromedial Hypotalamus Causes Hyperphagia and Alters the Hypothalamic Lipidomic Profile
por: Mera, Paula, et al.
Publicado: (2014)

Death show /
por: Casas, Luis, 1938-
Publicado: (1981)

Cannot write session to /tmp/vufind_sessions/sess_6q69dm20t5cu2sh4tsbe9a6afq