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Cucurbitacin B Down-Regulates TNF Receptor 1 Expression and Inhibits the TNF-α-Dependent Nuclear Factor κB Signaling Pathway in Human Lung Adenocarcinoma A549 Cells

Pro-inflammatory cytokines, such as tumor necrosis factor-α (TNF-α), induce the expression of intracellular adhesion molecule-1 (ICAM-1) by activating the nuclear factor κB (NF-κB) signaling pathway. In the present study, we found that cucurbitacin B decreased the expression of ICAM-1 in human lung...

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Detalles Bibliográficos
Autores principales:	Kusagawa, Eiichi, Okuda, Chiharu, Yamaguchi, Rikako, Nakano, Kaori, Miyake, Yasunobu, Kataoka, Takao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267118/ https://www.ncbi.nlm.nih.gov/pubmed/35806134 http://dx.doi.org/10.3390/ijms23137130

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