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The Clinical Dilemma of Esophagogastroduodenoscopy for Gastrointestinal Bleeding in Cardiovascular Disease Patients: A Nationwide-Based Retrospective Study

Performing esophagogastroduodenoscopy (EGD) in recently occurring peri-coronary artery disease (CAD) accident settings is always a dilemma. This study used the Taiwan National Health Insurance Research Database to identify patients with CAD and gastrointestinal bleeding who had received EGD or not b...

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Autores principales: Chang, Chao-Feng, Chien, Wu-Chien, Chung, Chi-Hsiang, Lin, Hsuan-Hwai, Huang, Tien-Yu, Chen, Peng-Jen, Chang, Wei-Kuo, Huang, Hsin-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267236/
https://www.ncbi.nlm.nih.gov/pubmed/35807050
http://dx.doi.org/10.3390/jcm11133765
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author Chang, Chao-Feng
Chien, Wu-Chien
Chung, Chi-Hsiang
Lin, Hsuan-Hwai
Huang, Tien-Yu
Chen, Peng-Jen
Chang, Wei-Kuo
Huang, Hsin-Hung
author_facet Chang, Chao-Feng
Chien, Wu-Chien
Chung, Chi-Hsiang
Lin, Hsuan-Hwai
Huang, Tien-Yu
Chen, Peng-Jen
Chang, Wei-Kuo
Huang, Hsin-Hung
author_sort Chang, Chao-Feng
collection PubMed
description Performing esophagogastroduodenoscopy (EGD) in recently occurring peri-coronary artery disease (CAD) accident settings is always a dilemma. This study used the Taiwan National Health Insurance Research Database to identify patients with CAD and gastrointestinal bleeding who had received EGD or not between 2000 and 2013.The final population included in this study was 15,147 individuals, with 3801 individuals having received EGD (study cohort group) and 11,346 individuals not having received EGD (comparison cohort group). We initially performed a sensitivity test for CAD recurrence-related factors using multivariable Cox regression during the tracking period. A relatively earlier EGD intervention within one week demonstrated a lower risk of CAD recurrence (adjusted HR = 0.712). Although there were no significant differences in the overall tracking period, the adjusted HR of CAD recurrence was still lower in patients in the EGD group. Furthermore, our findings revealed that there were no remarkably short intervals to CAD recurrence in the study group. The Kaplan–Meier survival curve demonstrated that individuals who underwent EGD were not associated with a significantly increased CAD recurrence rate compared with the control (Log-rank test, p = 0.255). CAD recurrence is always an issue in recent episodes of peri-CAD accident settings while receiving EGD. However, there is not a higher risk in comparison with the normal population in our study, and waiting periods may not be required.
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spelling pubmed-92672362022-07-09 The Clinical Dilemma of Esophagogastroduodenoscopy for Gastrointestinal Bleeding in Cardiovascular Disease Patients: A Nationwide-Based Retrospective Study Chang, Chao-Feng Chien, Wu-Chien Chung, Chi-Hsiang Lin, Hsuan-Hwai Huang, Tien-Yu Chen, Peng-Jen Chang, Wei-Kuo Huang, Hsin-Hung J Clin Med Article Performing esophagogastroduodenoscopy (EGD) in recently occurring peri-coronary artery disease (CAD) accident settings is always a dilemma. This study used the Taiwan National Health Insurance Research Database to identify patients with CAD and gastrointestinal bleeding who had received EGD or not between 2000 and 2013.The final population included in this study was 15,147 individuals, with 3801 individuals having received EGD (study cohort group) and 11,346 individuals not having received EGD (comparison cohort group). We initially performed a sensitivity test for CAD recurrence-related factors using multivariable Cox regression during the tracking period. A relatively earlier EGD intervention within one week demonstrated a lower risk of CAD recurrence (adjusted HR = 0.712). Although there were no significant differences in the overall tracking period, the adjusted HR of CAD recurrence was still lower in patients in the EGD group. Furthermore, our findings revealed that there were no remarkably short intervals to CAD recurrence in the study group. The Kaplan–Meier survival curve demonstrated that individuals who underwent EGD were not associated with a significantly increased CAD recurrence rate compared with the control (Log-rank test, p = 0.255). CAD recurrence is always an issue in recent episodes of peri-CAD accident settings while receiving EGD. However, there is not a higher risk in comparison with the normal population in our study, and waiting periods may not be required. MDPI 2022-06-29 /pmc/articles/PMC9267236/ /pubmed/35807050 http://dx.doi.org/10.3390/jcm11133765 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chang, Chao-Feng
Chien, Wu-Chien
Chung, Chi-Hsiang
Lin, Hsuan-Hwai
Huang, Tien-Yu
Chen, Peng-Jen
Chang, Wei-Kuo
Huang, Hsin-Hung
The Clinical Dilemma of Esophagogastroduodenoscopy for Gastrointestinal Bleeding in Cardiovascular Disease Patients: A Nationwide-Based Retrospective Study
title The Clinical Dilemma of Esophagogastroduodenoscopy for Gastrointestinal Bleeding in Cardiovascular Disease Patients: A Nationwide-Based Retrospective Study
title_full The Clinical Dilemma of Esophagogastroduodenoscopy for Gastrointestinal Bleeding in Cardiovascular Disease Patients: A Nationwide-Based Retrospective Study
title_fullStr The Clinical Dilemma of Esophagogastroduodenoscopy for Gastrointestinal Bleeding in Cardiovascular Disease Patients: A Nationwide-Based Retrospective Study
title_full_unstemmed The Clinical Dilemma of Esophagogastroduodenoscopy for Gastrointestinal Bleeding in Cardiovascular Disease Patients: A Nationwide-Based Retrospective Study
title_short The Clinical Dilemma of Esophagogastroduodenoscopy for Gastrointestinal Bleeding in Cardiovascular Disease Patients: A Nationwide-Based Retrospective Study
title_sort clinical dilemma of esophagogastroduodenoscopy for gastrointestinal bleeding in cardiovascular disease patients: a nationwide-based retrospective study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267236/
https://www.ncbi.nlm.nih.gov/pubmed/35807050
http://dx.doi.org/10.3390/jcm11133765
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