Functions of Breast Cancer Predisposition Genes: Implications for Clinical Management

Approximately 5–10% of all breast cancer (BC) cases are caused by germline pathogenic variants (GPVs) in various cancer predisposition genes (CPGs). The most common contributors to hereditary BC are BRCA1 and BRCA2, which are associated with hereditary breast and ovarian cancer (HBOC). ATM, BARD1, C...

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Detalles Bibliográficos
Autores principales: Yoshimura, Akiyo, Imoto, Issei, Iwata, Hiroji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267387/
https://www.ncbi.nlm.nih.gov/pubmed/35806485
http://dx.doi.org/10.3390/ijms23137481

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