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Hypercholesterolemia in Cancer and in Anorexia Nervosa: A Hypothesis for a Crosstalk

The relationship between cholesterol and cancer has been widely demonstrated. Clinical studies have shown changes in blood cholesterol levels in cancer patients. In parallel, basic research studies have shown that cholesterol is involved in the mechanisms of onset and progression of the disease. On...

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Autores principales: Gizzi, Giulia, Cataldi, Samuela, Mazzeschi, Claudia, Delvecchio, Elisa, Ceccarini, Maria Rachele, Codini, Michela, Albi, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267523/
https://www.ncbi.nlm.nih.gov/pubmed/35806470
http://dx.doi.org/10.3390/ijms23137466
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author Gizzi, Giulia
Cataldi, Samuela
Mazzeschi, Claudia
Delvecchio, Elisa
Ceccarini, Maria Rachele
Codini, Michela
Albi, Elisabetta
author_facet Gizzi, Giulia
Cataldi, Samuela
Mazzeschi, Claudia
Delvecchio, Elisa
Ceccarini, Maria Rachele
Codini, Michela
Albi, Elisabetta
author_sort Gizzi, Giulia
collection PubMed
description The relationship between cholesterol and cancer has been widely demonstrated. Clinical studies have shown changes in blood cholesterol levels in cancer patients. In parallel, basic research studies have shown that cholesterol is involved in the mechanisms of onset and progression of the disease. On the other hand, anorexic patients have high cholesterol levels and a high susceptibility to cancer. In this review, we first present a brief background on the relations among nutrition, eating disorders and cancer. Using several notable examples, we then illustrate the changes in cholesterol in cancer and in anorexia nervosa, providing evidence for their important relationship. Finally, we show a new possible link between cholesterol disorder in cancer and in anorexia nervosa.
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spelling pubmed-92675232022-07-09 Hypercholesterolemia in Cancer and in Anorexia Nervosa: A Hypothesis for a Crosstalk Gizzi, Giulia Cataldi, Samuela Mazzeschi, Claudia Delvecchio, Elisa Ceccarini, Maria Rachele Codini, Michela Albi, Elisabetta Int J Mol Sci Review The relationship between cholesterol and cancer has been widely demonstrated. Clinical studies have shown changes in blood cholesterol levels in cancer patients. In parallel, basic research studies have shown that cholesterol is involved in the mechanisms of onset and progression of the disease. On the other hand, anorexic patients have high cholesterol levels and a high susceptibility to cancer. In this review, we first present a brief background on the relations among nutrition, eating disorders and cancer. Using several notable examples, we then illustrate the changes in cholesterol in cancer and in anorexia nervosa, providing evidence for their important relationship. Finally, we show a new possible link between cholesterol disorder in cancer and in anorexia nervosa. MDPI 2022-07-05 /pmc/articles/PMC9267523/ /pubmed/35806470 http://dx.doi.org/10.3390/ijms23137466 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Gizzi, Giulia
Cataldi, Samuela
Mazzeschi, Claudia
Delvecchio, Elisa
Ceccarini, Maria Rachele
Codini, Michela
Albi, Elisabetta
Hypercholesterolemia in Cancer and in Anorexia Nervosa: A Hypothesis for a Crosstalk
title Hypercholesterolemia in Cancer and in Anorexia Nervosa: A Hypothesis for a Crosstalk
title_full Hypercholesterolemia in Cancer and in Anorexia Nervosa: A Hypothesis for a Crosstalk
title_fullStr Hypercholesterolemia in Cancer and in Anorexia Nervosa: A Hypothesis for a Crosstalk
title_full_unstemmed Hypercholesterolemia in Cancer and in Anorexia Nervosa: A Hypothesis for a Crosstalk
title_short Hypercholesterolemia in Cancer and in Anorexia Nervosa: A Hypothesis for a Crosstalk
title_sort hypercholesterolemia in cancer and in anorexia nervosa: a hypothesis for a crosstalk
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267523/
https://www.ncbi.nlm.nih.gov/pubmed/35806470
http://dx.doi.org/10.3390/ijms23137466
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