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Hypercholesterolemia in Cancer and in Anorexia Nervosa: A Hypothesis for a Crosstalk
The relationship between cholesterol and cancer has been widely demonstrated. Clinical studies have shown changes in blood cholesterol levels in cancer patients. In parallel, basic research studies have shown that cholesterol is involved in the mechanisms of onset and progression of the disease. On...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267523/ https://www.ncbi.nlm.nih.gov/pubmed/35806470 http://dx.doi.org/10.3390/ijms23137466 |
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author | Gizzi, Giulia Cataldi, Samuela Mazzeschi, Claudia Delvecchio, Elisa Ceccarini, Maria Rachele Codini, Michela Albi, Elisabetta |
author_facet | Gizzi, Giulia Cataldi, Samuela Mazzeschi, Claudia Delvecchio, Elisa Ceccarini, Maria Rachele Codini, Michela Albi, Elisabetta |
author_sort | Gizzi, Giulia |
collection | PubMed |
description | The relationship between cholesterol and cancer has been widely demonstrated. Clinical studies have shown changes in blood cholesterol levels in cancer patients. In parallel, basic research studies have shown that cholesterol is involved in the mechanisms of onset and progression of the disease. On the other hand, anorexic patients have high cholesterol levels and a high susceptibility to cancer. In this review, we first present a brief background on the relations among nutrition, eating disorders and cancer. Using several notable examples, we then illustrate the changes in cholesterol in cancer and in anorexia nervosa, providing evidence for their important relationship. Finally, we show a new possible link between cholesterol disorder in cancer and in anorexia nervosa. |
format | Online Article Text |
id | pubmed-9267523 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92675232022-07-09 Hypercholesterolemia in Cancer and in Anorexia Nervosa: A Hypothesis for a Crosstalk Gizzi, Giulia Cataldi, Samuela Mazzeschi, Claudia Delvecchio, Elisa Ceccarini, Maria Rachele Codini, Michela Albi, Elisabetta Int J Mol Sci Review The relationship between cholesterol and cancer has been widely demonstrated. Clinical studies have shown changes in blood cholesterol levels in cancer patients. In parallel, basic research studies have shown that cholesterol is involved in the mechanisms of onset and progression of the disease. On the other hand, anorexic patients have high cholesterol levels and a high susceptibility to cancer. In this review, we first present a brief background on the relations among nutrition, eating disorders and cancer. Using several notable examples, we then illustrate the changes in cholesterol in cancer and in anorexia nervosa, providing evidence for their important relationship. Finally, we show a new possible link between cholesterol disorder in cancer and in anorexia nervosa. MDPI 2022-07-05 /pmc/articles/PMC9267523/ /pubmed/35806470 http://dx.doi.org/10.3390/ijms23137466 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Gizzi, Giulia Cataldi, Samuela Mazzeschi, Claudia Delvecchio, Elisa Ceccarini, Maria Rachele Codini, Michela Albi, Elisabetta Hypercholesterolemia in Cancer and in Anorexia Nervosa: A Hypothesis for a Crosstalk |
title | Hypercholesterolemia in Cancer and in Anorexia Nervosa: A Hypothesis for a Crosstalk |
title_full | Hypercholesterolemia in Cancer and in Anorexia Nervosa: A Hypothesis for a Crosstalk |
title_fullStr | Hypercholesterolemia in Cancer and in Anorexia Nervosa: A Hypothesis for a Crosstalk |
title_full_unstemmed | Hypercholesterolemia in Cancer and in Anorexia Nervosa: A Hypothesis for a Crosstalk |
title_short | Hypercholesterolemia in Cancer and in Anorexia Nervosa: A Hypothesis for a Crosstalk |
title_sort | hypercholesterolemia in cancer and in anorexia nervosa: a hypothesis for a crosstalk |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267523/ https://www.ncbi.nlm.nih.gov/pubmed/35806470 http://dx.doi.org/10.3390/ijms23137466 |
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