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Health-Related Quality of Life following Surgery for Native and Prosthetic Valve Infective Endocarditis
Objectives: The objective of this study was to compare the long-term outcomes and health-related quality of life (HRQOL) of patients following surgery for infective native valve endocarditis (NVE) and prosthetic valve endocarditis (PVE). Methods: We retrospectively identified 633 consecutive patient...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267565/ https://www.ncbi.nlm.nih.gov/pubmed/35806881 http://dx.doi.org/10.3390/jcm11133599 |
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author | Saha, Shekhar Mladenova, Ralitsa Radner, Caroline Horke, Konstanze Maria Buech, Joscha Schnackenburg, Philipp Ali, Ahmad Peterss, Sven Juchem, Gerd Luehr, Maximilian Hagl, Christian Joskowiak, Dominik |
author_facet | Saha, Shekhar Mladenova, Ralitsa Radner, Caroline Horke, Konstanze Maria Buech, Joscha Schnackenburg, Philipp Ali, Ahmad Peterss, Sven Juchem, Gerd Luehr, Maximilian Hagl, Christian Joskowiak, Dominik |
author_sort | Saha, Shekhar |
collection | PubMed |
description | Objectives: The objective of this study was to compare the long-term outcomes and health-related quality of life (HRQOL) of patients following surgery for infective native valve endocarditis (NVE) and prosthetic valve endocarditis (PVE). Methods: We retrospectively identified 633 consecutive patients who had undergone surgery for infective endocarditis at our center between January 2005 and October 2018. The patients were interviewed, and the SF-36 survey was used to assess the HRQOL of survivors. Propensity score matching (2:1) was performed with data from a German reference population. Multivariable analysis incorporated binary logistic regression using a forward stepwise (conditional) model. Results: The median age of the cohort was 67 (55–74) years, and 75.6% were male. Operative mortality was 13.7% in the NVE group and 21.6% in the PVE group (p = 0.010). The overall survival at 1 year was 88.0% and was comparable between the groups. The physical health summary scores were 49 (40–55) for the NVE patients and 45 (37–52) for the PVE patients (p = 0.043). The median mental health summary scores were 52 (35–57) and 49 (41–56), respectively (p = 0.961). On comparison of the HRQOL to the reference population, the physical health summary scores were comparable. However, significant differences were observed with regard to the mental health summary scores (p = 0.005). Conclusions: Our study shows that there are significant differences in the various domains of HRQOL, not only between NVE and PVE patients, but also in comparison to healthy individuals. In addition to preoperative health status, it is important to consider the patient’s expectations regarding surgery. Further prospective studies are required. |
format | Online Article Text |
id | pubmed-9267565 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92675652022-07-09 Health-Related Quality of Life following Surgery for Native and Prosthetic Valve Infective Endocarditis Saha, Shekhar Mladenova, Ralitsa Radner, Caroline Horke, Konstanze Maria Buech, Joscha Schnackenburg, Philipp Ali, Ahmad Peterss, Sven Juchem, Gerd Luehr, Maximilian Hagl, Christian Joskowiak, Dominik J Clin Med Article Objectives: The objective of this study was to compare the long-term outcomes and health-related quality of life (HRQOL) of patients following surgery for infective native valve endocarditis (NVE) and prosthetic valve endocarditis (PVE). Methods: We retrospectively identified 633 consecutive patients who had undergone surgery for infective endocarditis at our center between January 2005 and October 2018. The patients were interviewed, and the SF-36 survey was used to assess the HRQOL of survivors. Propensity score matching (2:1) was performed with data from a German reference population. Multivariable analysis incorporated binary logistic regression using a forward stepwise (conditional) model. Results: The median age of the cohort was 67 (55–74) years, and 75.6% were male. Operative mortality was 13.7% in the NVE group and 21.6% in the PVE group (p = 0.010). The overall survival at 1 year was 88.0% and was comparable between the groups. The physical health summary scores were 49 (40–55) for the NVE patients and 45 (37–52) for the PVE patients (p = 0.043). The median mental health summary scores were 52 (35–57) and 49 (41–56), respectively (p = 0.961). On comparison of the HRQOL to the reference population, the physical health summary scores were comparable. However, significant differences were observed with regard to the mental health summary scores (p = 0.005). Conclusions: Our study shows that there are significant differences in the various domains of HRQOL, not only between NVE and PVE patients, but also in comparison to healthy individuals. In addition to preoperative health status, it is important to consider the patient’s expectations regarding surgery. Further prospective studies are required. MDPI 2022-06-22 /pmc/articles/PMC9267565/ /pubmed/35806881 http://dx.doi.org/10.3390/jcm11133599 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Saha, Shekhar Mladenova, Ralitsa Radner, Caroline Horke, Konstanze Maria Buech, Joscha Schnackenburg, Philipp Ali, Ahmad Peterss, Sven Juchem, Gerd Luehr, Maximilian Hagl, Christian Joskowiak, Dominik Health-Related Quality of Life following Surgery for Native and Prosthetic Valve Infective Endocarditis |
title | Health-Related Quality of Life following Surgery for Native and Prosthetic Valve Infective Endocarditis |
title_full | Health-Related Quality of Life following Surgery for Native and Prosthetic Valve Infective Endocarditis |
title_fullStr | Health-Related Quality of Life following Surgery for Native and Prosthetic Valve Infective Endocarditis |
title_full_unstemmed | Health-Related Quality of Life following Surgery for Native and Prosthetic Valve Infective Endocarditis |
title_short | Health-Related Quality of Life following Surgery for Native and Prosthetic Valve Infective Endocarditis |
title_sort | health-related quality of life following surgery for native and prosthetic valve infective endocarditis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267565/ https://www.ncbi.nlm.nih.gov/pubmed/35806881 http://dx.doi.org/10.3390/jcm11133599 |
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