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DJ-1 Alleviates Neuroinflammation and the Related Blood-Spinal Cord Barrier Destruction by Suppressing NLRP3 Inflammasome Activation via SOCS1/Rac1/ROS Pathway in a Rat Model of Traumatic Spinal Cord Injury

DJ-1 has been shown to play essential roles in neuronal protection and anti-inflammation in nervous system diseases. This study aimed to explore how DJ-1 regulates neuroinflammation after traumatic spinal cord injury (t-SCI). The rat model of spinal cord injury was established by the clamping method...

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Detalles Bibliográficos
Autores principales: Cai, Lingxin, Gao, Liansheng, Zhang, Guoqiang, Zeng, Hanhai, Wu, Xinyan, Tan, Xiaoxiao, Qian, Cong, Chen, Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267719/
https://www.ncbi.nlm.nih.gov/pubmed/35807002
http://dx.doi.org/10.3390/jcm11133716